ARG42887
anti-RPS6KA6 / RSK4 phospho (Ser232) antibody
anti-RPS6KA6 / RSK4 phospho (Ser232) antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Human,Mouse
Overview
| Product Description | Rabbit Polyclonal antibody recognizes RPS6KA6 / RSK4 phospho (Ser232) |
|---|---|
| Tested Reactivity | Hu, Ms |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | RPS6KA6 / RSK4 |
| Antigen Species | Human |
| Immunogen | Phosphospecific peptide around Ser232 of Human RPS6KA6 / RSK4. |
| Conjugation | Un-conjugated |
| Alternate Names | Ribosomal S6 kinase 4; pp90RSK4; p90-RSK 6; p90RSK6; RSK-4; PP90RSK4; S6K-alpha-6; EC 2.7.11.1; 90 kDa ribosomal protein S6 kinase 6; RSK4; Ribosomal protein S6 kinase alpha-6 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Positive Control | HeLa | ||||||
| Observed Size | ~ 84 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | 50 nM Tris-Glycine (pH 7.4), 0.15M NaCl, 0.01% Sodium azide, 40% Glycerol and 0.05% BSA. |
| Preservative | 0.01% Sodium azide |
| Stabilizer | 40% Glycerol and 0.05% BSA |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q7TPS0 Mouse Ribosomal protein S6 kinase alpha-6 Swiss-port # Q9UK32 Human Ribosomal protein S6 kinase alpha-6 |
|---|---|
| Gene Symbol | RPS6KA6 |
| Gene Full Name | ribosomal protein S6 kinase, 90kDa, polypeptide 6 |
| Background | This gene encodes a member of ribosomal S6 kinase family, serine-threonine protein kinases which are regulated by growth factors. The encoded protein may be distinct from other members of this family, however, as studies suggest it is not growth factor dependent and may not participate in the same signaling pathways. [provided by RefSeq, Jan 2010] |
| Function | Constitutively active serine/threonine-protein kinase that exhibits growth-factor-independent kinase activity and that may participate in p53/TP53-dependent cell growth arrest signaling and play an inhibitory role during embryogenesis. [UniProt] |
| Cellular Localization | Cytoplasm, cytosol. Nucleus. Note=Predominantly cytosolic. [UniProt] |
| Calculated MW | 84 kDa |
| PTM | Phosphorylated at Ser-232, Ser-372, and Ser-389 in serum-starved cells. [UniProt] |
