ARG42159
anti-RTCB / HSPC117 antibody
anti-RTCB / HSPC117 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Overview
Product Description | Rabbit Polyclonal antibody recognizes RTCB / HSPC117 |
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Tested Reactivity | Hu |
Predict Reactivity | Ms, Rat, Cow, Dog, Gpig, Hrs, Rb, Zfsh |
Tested Application | IHC-P, WB |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Target Name | RTCB / HSPC117 |
Antigen Species | Human |
Immunogen | Synthetic peptide around the N-terminal region of Human RTCB / HSPC117. (within the following region: PEAVV SPGGV GFDIN CGVRL LRTNL DESDV QPVKE QLAQA MFDHI PVGVG) |
Conjugation | Un-conjugated |
Alternate Names | EC 6.5.1.3; HSPC117; DJ149A16.6; C22orf28; tRNA-splicing ligase RtcB homolog; FAAP |
Application Instructions
Predict Reactivity Note | Predicted Homology Based on Immunogen Sequence: Cow: 100%; Dog: 100%; Guinea pig: 100%; Horse: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93% | ||||||
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Application Suggestion |
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Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
Positive Control | 293T | ||||||
Observed Size | ~ 55 kDa |
Properties
Form | Liquid |
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Purification | Affinity purified. |
Buffer | PBS, 0.09% (w/v) Sodium azide and 2% Sucrose. |
Preservative | 0.09% (w/v) Sodium azide |
Stabilizer | 2% Sucrose |
Concentration | Batch dependent: 0.5 - 1 mg/ml |
Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Database Links | |
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Gene Symbol | RTCB |
Gene Full Name | RNA 2',3'-cyclic phosphate and 5'-OH ligase |
Function | Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs. [UniProt] |
Cellular Localization | Nucleus. Cytoplasm. Note=Enters into the nucleus in case of active transcription while it accumulates in cytosol when transcription level is low. [UniProt] |
Calculated MW | 55 kDa |