ARG44066
anti-RUFY3 antibody
anti-RUFY3 antibody for Flow cytometry,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal recognizes RUFY3 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | FACS, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | RUFY3 |
| Antigen Species | Human |
| Immunogen | Human RUFY3 recombinant protein (Position: M1-H469). |
| Conjugation | Un-conjugated |
| Alternate Names | RUFY3; RUN And FYVE Domain Containing 3; KIAA0871; ZFYVE30; RIPx; Single Axon-Regulated Protein; Single Axon-Related 1; Protein RUFY3; Singar1; RUN And FYVE Domain-Containing Protein 3; Rap2 Interacting Protein X; Rap2-Interacting Protein X; SINGAR1; Singar; RIPX |
Application Instructions
| Application Suggestion |
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| Application Note | The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose. |
| Preservative | 0.05% Sodium azide |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | RUFY3 |
| Gene Full Name | RUN And FYVE Domain Containing 3 |
| Background | This gene encodes a RPIP8, UNC-14, and NESCA domain-containing protein that is required for maintenance of neuronal polarity. In addition, it has been implicated in mediation of gastric cancer cell migration and invasion via interaction with P21-activated kinase-1, which promotes its expression. The encoded protein localizes to F-actin-enriched invadopodia to induce formation of protrusions, thereby facilitating cell migration. Alternative splicing results in multiple transcript variants. |
| Function | Plays a role in the formation of F-actin-enriched protrusive structures at the cell periphery. |
| Cellular Localization | Cell junction, Cell projection, Cytoplasm, Membrane |
| Calculated MW | 53 kDa |
| PTM | Phosphoprotein |
