ARG44009
anti-RXYLT1 antibody
anti-RXYLT1 antibody for ELISA,Flow cytometry,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes RXYLT1 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | ELISA, FACS, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | RXYLT1 |
| Antigen Species | Human |
| Immunogen | Human RXYLT1 recombinant protein |
| Expression System | E.coli |
| Conjugation | Un-conjugated |
| Protein Full Name | Ribitol-5-phosphate xylosyltransferase 1 |
| Alternate Names | RXYLT1; Ribitol Xylosyltransferase 1; Transmembrane Protein 5; HP10481; TMEM5; UDP-D-Xylose:Ribitol-5-Phosphate Beta1,4-Xylosyltransferase; Ribitol-5-Phosphate Xylosyltransferase 1; Type II Membrane Protein; EC 2.4.2.61; MDDGA10 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Buffer | 0.9% NaCl, 0.2% Na2HPO4 and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | RXYLT1 |
| Gene Full Name | Ribitol Xylosyltransferase 1 |
| Background | This gene encodes a type II transmembrane protein that is thought to have glycosyltransferase function. Mutations in this gene result in cobblestone lissencephaly. Alternative splicing results in multiple transcript variants encoding different isoforms. |
| Function | Acts as a UDP-D-xylose:ribitol-5-phosphate beta1,4-xylosyltransferase, which catalyzes the transfer of UDP-D-xylose to ribitol 5-phosphate (Rbo5P) to form the Xylbeta1-4Rbo5P linkage on O-mannosyl glycan (PubMed:27733679, PubMed:29477842) (Probable). Participates in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity (PubMed:25279699, PubMed:27601598, PubMed:27733679) (Probable). |
| Cellular Localization | Golgi apparatus,Membrane |
| Calculated MW | 51 kDa |
Images (4) Click the Picture to Zoom In
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ARG44009 anti-RXYLT1 antibody WB image
Western blot: MCF-7 and HEL stained with ARG44009 anti-RXYLT1 antibody at 0.5 μg/mL dilution.
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ARG44009 anti-RXYLT1 antibody FACS image
Flow Cytometry: Daudi cells stained with ARG44009 anti-RXYLT1 antibody (blue) at 1 μg/1x10^6 cells dilution.
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ARG44009 anti-RXYLT1 antibody WB image
Western blot: Rat brain stained with ARG44009 anti-RXYLT1 antibody at 0.5 μg/mL dilution.
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ARG44009 anti-RXYLT1 antibody WB image
Western blot: Mouse brain stained with ARG44009 anti-RXYLT1 antibody at 0.5 μg/mL dilution.
