ARG52416

anti-Retinoid X Receptor gamma antibody [1373]

anti-Retinoid X Receptor gamma antibody [1373] for Western blot and Human,Rat

Cancer antibody; Gene Regulation antibody; Signaling Transduction antibody

Overview

Product Description Mouse Monoclonal antibody [1373] recognizes Retinoid X Receptor gamma
Tested Reactivity Hu, Rat
Predict Reactivity Ms, Bov, NHuPrm
Tested Application WB
Host Mouse
Clonality Monoclonal
Clone 1373
Isotype IgG1
Target Name Retinoid X Receptor gamma
Antigen Species Human
Immunogen Synthetic peptide corresponding to amino acid residues from the hinge region conjugated to KLH
Conjugation Un-conjugated
Alternate Names NR2B3; Nuclear receptor subfamily 2 group B member 3; Retinoid X receptor gamma; Retinoic acid receptor RXR-gamma; RXRC

Application Instructions

Application Suggestion
Tested Application Dilution
WB1:1000
Application Note Specific for the ~48k RXR-γ isotype.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Protein G purified
Buffer 10 mM HEPES (pH 7.5), 150 mM NaCl, 0.1 mg/ml BSA and 50% Glycerol
Stabilizer 0.1 mg/ml BSA, 50% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 6258 Human RXRG

GeneID: 83574 Rat RXRG

Swiss-port # P48443 Human Retinoic acid receptor RXR-gamma

Swiss-port # Q5BJR8 Rat Retinoic acid receptor RXR-gamma

Gene Symbol RXRG
Gene Full Name retinoid X receptor, gamma
Background Retinoic acid (RA; active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells (Joshi et al., 2005). The Retinoid X Receptors (RXRs) family (RXRα, β and γ) preferentially bind 9-cis-RA and regulate gene transcription by forming heterodimers with a second family of RA receptors. RAs have been suggested to potentially play a therapeutic role in cervical cancer (Abu et al., 2005). RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors (Lane and Bailey, 2005).
Research Area Cancer antibody; Gene Regulation antibody; Signaling Transduction antibody
Calculated MW 51 kDa