ARG45082
anti-Robo2 antibody
anti-Robo2 antibody for Western blot and Chicken,Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes Robo2 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat, Chk |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | Robo2 |
| Antigen Species | Human |
| Immunogen | Robo2 synthetic peptide (coupled to carrier protein) corresponds to amino acids in the C-terminal region of human Robo2. This sequence has significant homology to the same region in rat and mouse Robo2, and has low homology to other Robo family members. |
| Conjugation | Un-conjugated |
| Alternate Names | ROBO2; Roundabout Guidance Receptor 2; KIAA1568; Roundabout Homolog 2; Roundabout, Axon Guidance Receptor, Homolog 2 (Drosophila); Roundabout (Axon Guidance Receptor, Drosophila) Homolog 2; Roundabout, Axon Guidance Receptor, Homolog 2; SAX3 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Antigen Affinity Purified. |
| Buffer | PBS, 0.05% NaN3, 50% Glycerol and 0.1 % BSA. |
| Stabilizer | 50% Glycerol and 0.1 % BSA |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | ROBO2 |
| Gene Full Name | Roundabout Guidance Receptor 2 |
| Background | The protein encoded by this gene belongs to the ROBO family, part of the immunoglobulin superfamily of proteins that are highly conserved from fly to human. The encoded protein is a transmembrane receptor for the slit homolog 2 protein and functions in axon guidance and cell migration. Mutations in this gene are associated with vesicoureteral reflux, characterized by the backward flow of urine from the bladder into the ureters or the kidney. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014] |
| Function | Receptor for SLIT2, and probably SLIT1, which are thought to act as molecular guidance cue in cellular migration, including axonal navigation at the ventral midline of the neural tube and projection of axons to different regions during neuronal development. [Uniprot] |
| Cellular Localization | Membrane. [Uniprot] |
| Calculated MW | 151 kDa |
| PTM | Disulfide bond, Glycoprotein, Phosphoprotein. [Uniprot] |
