ARG59513

anti-S100A11 antibody

anti-S100A11 antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections,ICC/IF and Human

Overview

Product Description Rabbit Polyclonal antibody recognizes S100A11
Tested Reactivity Hu
Predict Reactivity Ms, Rat
Tested Application ICC/IF, IHC-P, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name S100A11
Antigen Species Human
Immunogen Recombinant fusion protein corresponding to aa. 1-105 of Human S100A11 (NP_005611.1).
Conjugation Un-conjugated
Alternate Names S100 calcium-binding protein A11; MLN70; MLN 70; Protein S100-C; HEL-S-43; Metastatic lymph node gene 70 protein; Protein S100-A11; S100C; Calgizzarin

Application Instructions

Application Suggestion
Tested Application Dilution
ICC/IF1:50 - 1:200
IHC-P1:50 - 1:200
WB1:500 - 1:2000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control BxPC3 and 22RV1
Observed Size 12 kDa

Properties

Form Liquid
Purification Affinity purified.
Buffer PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
Preservative 0.02% Sodium azide
Stabilizer 50% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 6282 Human S100A11

Swiss-port # P31949 Human Protein S100-A11

Gene Symbol S100A11
Gene Full Name S100 calcium binding protein A11
Background The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis. [provided by RefSeq, Jul 2008]
Function Facilitates the differentiation and the cornification of keratinocytes. [UniProt]
Cellular Localization Cytoplasm. Nucleus. [UniProt]
Calculated MW 12 kDa
PTM Phosphorylation at Thr-10 by PRKCA significantly suppresses homodimerization and promotes association with NCL/nucleolin which induces nuclear translocation. [UniProt]