ARG66520

anti-S100A6 antibody

anti-S100A6 antibody for IHC-Formalin-fixed paraffin-embedded sections and Human

Overview

Product Description Mouse Monoclonal antibody recognizes S100A6
Tested Reactivity Hu
Tested Application IHC-P
Host Mouse
Clonality Monoclonal
Isotype IgG1, kappa
Target Name S100A6
Antigen Species Human
Immunogen Synthetic peptide derived from Human S100A6.
Conjugation Un-conjugated
Alternate Names S100 calcium-binding protein A6; PRA; MLN 4; 5B10; Prolactin receptor-associated protein; CACY; Growth factor-inducible protein 2A9; Protein S100-A6; Calcyclin; CABP; 2A9

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P1:100 - 1:500
Application Note IHC-P: Antigen Retrieval: Tris/EDTA buffer (pH 8.0) was used.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Affinity purification with immunogen.
Buffer PBS, 0.02% Sodium azide, 50% Glycerol and 0.5% BSA.
Preservative 0.02% Sodium azide
Stabilizer 50% Glycerol and 0.5% BSA
Concentration 1 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 6277 Human S100A6

Swiss-port # P06703 Human Protein S100-A6

Gene Symbol S100A6
Gene Full Name S100 calcium binding protein A6
Background The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-dependent insulin release, stimulation of prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of this gene have been implicated in melanoma. [provided by RefSeq, Jul 2008]
Function May function as calcium sensor and modulator, contributing to cellular calcium signaling. May function by interacting with other proteins, such as TPR-containing proteins, and indirectly play a role in many physiological processes such as the reorganization of the actin cytoskeleton and in cell motility. Binds 2 calcium ions. Calcium binding is cooperative. [UniProt]
Cellular Localization Nucleus envelope. Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side. [UniProt]
Calculated MW 10 kDa
PTM The N-terminus is blocked. [UniProt]