ARG44927
anti-SCAMP5 antibody
anti-SCAMP5 antibody for IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation,Western blot and Human,Mouse
Overview
| Product Description | Mouse Monoclonal antibody recognizes SCAMP5 |
|---|---|
| Tested Reactivity | Hu, Ms |
| Tested Application | IHC-P, IP, WB |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Target Name | SCAMP5 |
| Antigen Species | Human |
| Epitope | LPKFIPLKPC FYQDFEADIP |
| Conjugation | Un-conjugated |
| Alternate Names | SCAMP5; Secretory Carrier Membrane Protein 5; Secretory Carrier-Associated Membrane Protein 5; MGC24969; HSCAMP5 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Protein A purification |
| Buffer | PBS with 0.09% sodium azide |
| Preservative | 0.09% sodium azide |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | SCAMP5 |
|---|---|
| Gene Full Name | Secretory Carrier Membrane Protein 5 |
| Background | Involved in positive regulation of cytokine production; regulation of vesicle-mediated transport; and response to endoplasmic reticulum stress. Located in Golgi apparatus; plasma membrane; and recycling endosome membrane. Is integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022] |
| Function | Required for the calcium-dependent exocytosis of signal sequence-containing cytokines such as CCL5. Probably acts in cooperation with the SNARE machinery. May play a role in accumulation of expanded polyglutamine (polyQ) protein huntingtin (HTT) in case of endoplasmic reticulum stress by inhibiting the endocytosis pathway. [UniProt] |
| Cellular Localization | Cell membrane, Cytoplasmic vesicle, Endosome, Golgi apparatus, Membrane, Synapse. [UniProt] |
| Calculated MW | 26 kDa |
