ARG43455
anti-SCARA5 antibody
anti-SCARA5 antibody for ICC/IF,Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes SCARA5 |
|---|---|
| Tested Reactivity | Hu |
| Predict Reactivity | Ms, Rat, Bov, Chk |
| Tested Application | ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | SCARA5 |
| Antigen Species | Human |
| Immunogen | A 17-amino acid synthetic peptide within aa. 350 - 400 of Human SCARA5. |
| Conjugation | Un-conjugated |
| Protein Full Name | Scavenger receptor class A member 5 |
| Alternate Names | Tesr; NET33; Scavenger receptor class A member 5; Scavenger receptor hlg |
Application Instructions
| Predict Reactivity Note | Based on sequence homology analysis: Bovine (100%), Mouse (88%), Chicken: (86%), Rat (80%) | ||||||
|---|---|---|---|---|---|---|---|
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Positive Control | Human Liver Tissue Lysate, HepG2 | ||||||
| Observed Size | ~ 52 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | PBS and 0.02% Sodium azide. |
| Preservative | 0.02% Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q6ZMJ2 Human Scavenger receptor class A member 5 |
|---|---|
| Gene Symbol | SCARA5 |
| Gene Full Name | scavenger receptor class A member 5 |
| Background | SCARA5 (Scavenger Receptor Class A Member 5) is a Protein Coding gene. Diseases associated with SCARA5 include Prostate Leiomyosarcoma and Prostate Stromal Sarcoma. Among its related pathways are Binding and Uptake of Ligands by Scavenger Receptors and Vesicle-mediated transport. Gene Ontology (GO) annotations related to this gene include scavenger receptor activity and ferritin receptor activity. An important paralog of this gene is MSR1. [GeneCards] |
| Function | Ferritin receptor that mediates non-transferrin-dependent delivery of iron. Mediates cellular uptake of ferritin-bound iron by stimulating ferritin endocytosis from the cell surface with consequent iron delivery within the cell. Delivery of iron to cells by ferritin is required for the development of specific cell types, suggesting the existence of cell type-specific mechanisms of iron traffic in organogenesis, which alternatively utilize transferrin or non-transferrin iron delivery pathways. Ferritin mediates iron uptake in capsule cells of the developing kidney. Binds preferrentially ferritin light chain (FTL) compared to heavy chain (FTH1). |
| Cellular Localization | Cell membrane, Membrane |
| Calculated MW | 54 kDa |
| PTM | Disulfide bond, Glycoprotein |
