ARG10899

anti-SCP3 antibody [Cor 10G11/7]

anti-SCP3 antibody [Cor 10G11/7] for ELISA,ICC/IF,Immunohistochemistry,Western blot and Hamster,Mouse,Zebrafish

Overview

Product Description Mouse Monoclonal antibody [Cor 10G11/7] recognizes SCP3
Tested Reactivity Ms, Hm, Zfsh
Tested Application ELISA, ICC/IF, IHC, WB
Host Mouse
Clonality Monoclonal
Clone Cor 10G11/7
Target Name SCP3
Antigen Species Hamster
Immunogen Hamster SCP3 protein (expressed as 6x His fusion in bacteria and purified on a Talon under denaturing conditions).
Conjugation Un-conjugated
Alternate Names Synaptonemal complex protein 3; SPGF4; COR1; SCP-3; SCP3

Application Instructions

Application Suggestion
Tested Application Dilution
ELISAAssay-dependent
ICC/IFAssay-dependent
IHCAssay-dependent
WBAssay-dependent
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purified by affinity chromatography.
Buffer PBS and 0.02% Sodium azide.
Preservative 0.02% Sodium azide
Concentration 1 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 101825388 Hamster SYCP3

GeneID: 20962 Mouse SYCP3

Swiss-port # P70281 Mouse Synaptonemal complex protein 3

Swiss-port # Q60547 Hamster Synaptonemal complex protein 3

Gene Symbol SYCP3
Gene Full Name synaptonemal complex protein 3
Background This gene encodes an essential structural component of the synaptonemal complex. This complex is involved in synapsis, recombination and segregation of meiotic chromosomes. Mutations in this gene are associated with azoospermia in males and susceptibility to pregnancy loss in females. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, May 2010]
Function Component of the transverse filaments of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. Has an essential meiotic function in spermatogenesis. May be important for testis development. Required for efficient phosphorylation of HORMAD1 and HORMAD2 (By similarity). [UniProt]
Calculated MW 28 kDa
PTM Phosphorylated. [UniProt]