ARG10899
anti-SCP3 antibody [Cor 10G11/7]
anti-SCP3 antibody [Cor 10G11/7] for ELISA,ICC/IF,Immunohistochemistry,Western blot and Hamster,Mouse,Zebrafish
Overview
Product Description | Mouse Monoclonal antibody [Cor 10G11/7] recognizes SCP3 |
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Tested Reactivity | Ms, Hm, Zfsh |
Tested Application | ELISA, ICC/IF, IHC, WB |
Host | Mouse |
Clonality | Monoclonal |
Clone | Cor 10G11/7 |
Target Name | SCP3 |
Antigen Species | Hamster |
Immunogen | Hamster SCP3 protein (expressed as 6x His fusion in bacteria and purified on a Talon under denaturing conditions). |
Conjugation | Un-conjugated |
Alternate Names | Synaptonemal complex protein 3; SPGF4; COR1; SCP-3; SCP3 |
Application Instructions
Application Suggestion |
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Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
Form | Liquid |
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Purification | Purified by affinity chromatography. |
Buffer | PBS and 0.02% Sodium azide. |
Preservative | 0.02% Sodium azide |
Concentration | 1 mg/ml |
Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Database Links |
GeneID: 101825388 Hamster SYCP3 |
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Gene Symbol | SYCP3 |
Gene Full Name | synaptonemal complex protein 3 |
Background | This gene encodes an essential structural component of the synaptonemal complex. This complex is involved in synapsis, recombination and segregation of meiotic chromosomes. Mutations in this gene are associated with azoospermia in males and susceptibility to pregnancy loss in females. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, May 2010] |
Function | Component of the transverse filaments of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. Has an essential meiotic function in spermatogenesis. May be important for testis development. Required for efficient phosphorylation of HORMAD1 and HORMAD2 (By similarity). [UniProt] |
Calculated MW | 28 kDa |
PTM | Phosphorylated. [UniProt] |