ARG41315

anti-SEC63 antibody

anti-SEC63 antibody for Western blot and Human

Overview

Product Description Rabbit Polyclonal antibody recognizes SEC63
Tested Reactivity Hu
Predict Reactivity Ms, Rat, Cow, Dog, Gpig, Hrs, Rb, Zfsh
Tested Application WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name SEC63
Antigen Species Human
Immunogen Synthetic peptide around the C-terminal region of Human SEC63. (within the following region: WWLYIADRKEQTLISMPYHVCTLKDTEEVELKFPAPGKPGNYQYTVFLRS)
Conjugation Un-conjugated
Alternate Names DNAJC23; SEC63L; PRO2507; ERdj2; Translocation protein SEC63 homolog

Application Instructions

Predict Reactivity Note Predicted Homology Based On Immunogen Sequence: Cow: 100%; Dog: 100%; Guinea pig: 100%; Horse: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 85%
Application Suggestion
Tested Application Dilution
WB1 - 3 µg/ml
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control HepG2

Properties

Form Liquid
Purification Purification with Protein A.
Buffer PBS, 0.09% (w/v) Sodium azide and 2% Sucrose.
Preservative 0.09% (w/v) Sodium azide
Stabilizer 2% Sucrose
Concentration Batch dependent: 0.5 - 1 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 11231 Human SEC63

Swiss-port # Q9UGP8 Human Translocation protein SEC63 homolog

Gene Symbol SEC63
Gene Full Name SEC63 homolog, protein translocation regulator
Background The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC62 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER. [provided by RefSeq, Jul 2008]
Function Required for integral membrane and secreted preprotein translocation across the endoplasmic reticulum membrane. [UniProt]
Cellular Localization Endoplasmic reticulum membrane; Multi-pass membrane protein. [UniProt]
Calculated MW 88 kDa