ARG63644
anti-SIAHBP1 / FIR antibody
anti-SIAHBP1 / FIR antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Gene Regulation antibody
Overview
Product Description | Goat Polyclonal antibody recognizes SIAHBP1 / FIR |
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Tested Reactivity | Hu |
Predict Reactivity | Ms, Rat, Cow, Dog |
Tested Application | IHC-P, WB |
Specificity | This antibody is expected to recognise all reported human isoforms (as represented by NP_510965.1; NP_055096.2; NP_001129505.1) |
Host | Goat |
Clonality | Polyclonal |
Isotype | IgG |
Target Name | SIAHBP1 / FIR |
Antigen Species | Human |
Immunogen | C-YDQERFDNSDLSA |
Conjugation | Un-conjugated |
Alternate Names | FIR; RoBPI; Poly; SIAHBP1; Siah-binding protein 1; U; 60 kDa poly; FUSE-binding protein-interacting repressor; VRJS; Siah-BP1; Ro-binding protein 1; RoBP1; FBP-interacting repressor |
Application Instructions
Application Suggestion |
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Application Note | WB: Recommend incubate at RT for 1h. IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
Form | Liquid |
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Purification | Purified from goat serum by antigen affinity chromatography. |
Buffer | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
Preservative | 0.02% Sodium azide |
Stabilizer | 0.5% BSA |
Concentration | 0.5 mg/ml |
Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Database Links |
Swiss-port # Q9UHX1 Human Poly(U)-binding-splicing factor PUF60 |
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Background | The protein encoded by this gene is a Ro RNP-binding protein. It interacts with Ro RNPs and their interaction is thought to represent a gain of function for Ro RNPs. This protein also forms a ternary complex with far upstream element (FUSE) and FUSE-binding protein. It can repress a c-myc reporter via the FUSE. It is also known to target transcription factor IIH and inhibit activated transcription. This gene is implicated in the xeroderma pigmentosum disorder. There are two alternatively spliced transcript variants of this gene encoding different isoforms. There seems to be evidence of multiple polyadenylation sites for this gene. [provided by RefSeq, Jul 2008] |
Research Area | Gene Regulation antibody |
Calculated MW | 60 kDa |