ARG54661
anti-SIRT5 antibody
anti-SIRT5 antibody for ELISA,Western blot and Human,Mouse
Cell Biology and Cellular Response antibody; Gene Regulation antibody; Metabolism antibody
Overview
| Product Description | Chicken Polyclonal antibody recognizes SIRT5 |
|---|---|
| Tested Reactivity | Hu, Ms |
| Tested Application | ELISA, WB |
| Host | Chicken |
| Clonality | Polyclonal |
| Isotype | IgY |
| Target Name | SIRT5 |
| Immunogen | Synthetic peptide (17 aa) within the last 50 aa of Human SIRT5. |
| Conjugation | Un-conjugated |
| Alternate Names | SIR2L5; Regulatory protein SIR2 homolog 5; EC 3.5.1.-; NAD-dependent protein deacylase sirtuin-5, mitochondrial; SIR2-like protein 5 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Positive Control | Human Liver Tissue Lysate |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | PBS and 0.02% Sodium azide |
| Preservative | 0.02% Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q8K2C6 Mouse NAD-dependent protein deacylase sirtuin-5, mitochondrial Swiss-port # Q9NXA8 Human NAD-dependent protein deacylase sirtuin-5, mitochondrial |
|---|---|
| Gene Symbol | SIRT5 |
| Gene Full Name | sirtuin 5 |
| Background | SIRT5 Antibody: The Silent Information Regulator (SIR2) family of genes are highly conserved from prokaryotes to eukaryotes and have important functions in the regulation of metabolism, growth and differentiation, inflammation, cellular survival, as well as in senescence and lifespan extension. Sirtuins, including SIRT1-7, are human homologs of yeast Sir2p. Sirtuins are NAD+-dependent histone/protein deacetylases (HDAC) which regulate cellular metabolism, e.g. energy metabolism, and thereby are associated with aging and several age-related diseases. SIRT5 localizes to mitochondria, deacetylates carbamoyl phosphate synthetase 1, and is involved in the regulation of the urea cycle. | |
| Research Area | Cell Biology and Cellular Response antibody; Gene Regulation antibody; Metabolism antibody |
| Calculated MW | 34 kDa |
