ARG63687

anti-SLC18A2 / VMAT2 antibody

anti-SLC18A2 / VMAT2 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse

Neuroscience antibody

Overview

Product Description Goat Polyclonal antibody recognizes SLC18A2 / VMAT2
Tested Reactivity Hu, Ms
Predict Reactivity Cow, Rat, Dog, Pig
Tested Application IHC-P, WB
Host Goat
Clonality Polyclonal
Isotype IgG
Target Name SLC18A2 / VMAT2
Antigen Species Human
Immunogen C-SYPIGEDEESESD
Conjugation Un-conjugated
Alternate Names VAT2; VMAT2; Solute carrier family 18 member 2; SVMT; Synaptic vesicular amine transporter; SVAT; Vesicular amine transporter 2; Monoamine transporter

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-PAssay - dependent
WB1 - 3 µg/ml
Application Note WB: Recommend incubate at RT for 1h.
IHC-P: Antigen Retrieval: Heat mediation was performed in Citrate buffer (pH 6.0).
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purified from goat serum by antigen affinity chromatography.
Buffer Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA.
Preservative 0.02% Sodium azide
Stabilizer 0.5% BSA
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 214084 Mouse SLC18A2

GeneID: 6571 Human SLC18A2

Swiss-port # Q05940 Human Synaptic vesicular amine transporter

Swiss-port # Q8BRU6 Mouse Synaptic vesicular amine transporter

Background The vesicular monoamine transporter acts to accumulate cytosolic monoamines into synaptic vesicles, using the proton gradient maintained across the synaptic vesicular membrane. Its proper function is essential to the correct activity of the monoaminergic systems that have been implicated in several human neuropsychiatric disorders. The transporter is a site of action of important drugs, including reserpine and tetrabenazine (summary by Peter et al., 1993 [PubMed 7905859]). See also SLC18A1 (MIM 193002).[supplied by OMIM, Jan 2011]
Research Area Neuroscience antibody
Calculated MW 56 kDa