ARG41960
anti-SLC25A28 / Mitoferrin 2 antibody
anti-SLC25A28 / Mitoferrin 2 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes SLC25A28 / Mitoferrin 2 |
|---|---|
| Tested Reactivity | Hu |
| Predict Reactivity | Ms, Rat, Cow, Dog, Gpig, Hrs, Rb |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | SLC25A28 / Mitoferrin 2 |
| Antigen Species | Human |
| Immunogen | Synthetic peptide around the C-terminal region of Human SLC25A28 / Mitoferrin 2. (within the following region: NTQES LALNS HITGH ITGMA SAFRT VYQVG GVTAY FRGVQ ARVIY QIPST) |
| Conjugation | Un-conjugated |
| Alternate Names | MFRN2; NPD016; Mitochondrial RNA-splicing protein 3/4 homolog; Mitoferrin-2; MRS3/4; hMRS3/4; MRS4L; Solute carrier family 25 member 28; Mitochondrial iron transporter 2 |
Application Instructions
| Predict Reactivity Note | Predicted Homology Based On Immunogen Sequence: Cow: 86%; Dog: 93%; Guinea pig: 93%; Horse: 93%; Mouse: 93%; Rabbit: 93%; Rat: 93% | ||||||
|---|---|---|---|---|---|---|---|
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Positive Control | MCF7 | ||||||
| Observed Size | ~ 33 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS, 0.09% (w/v) Sodium azide and 2% Sucrose. |
| Preservative | 0.09% (w/v) Sodium azide |
| Stabilizer | 2% Sucrose |
| Concentration | Batch dependent: 0.5 - 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | SLC25A28 |
| Gene Full Name | solute carrier family 25 (mitochondrial iron transporter), member 28 |
| Function | Mitochondrial iron transporter that mediates iron uptake. Probably required for heme synthesis of hemoproteins and Fe-S cluster assembly in non-erythroid cells. The iron delivered into the mitochondria, presumably as Fe(2+), is then probably delivered to ferrochelatase to catalyze Fe(2+) incorporation into protoprophyrin IX to make heme (By similarity). [UniProt] |
| Cellular Localization | Mitochondrion inner membrane; Multi-pass membrane protein. Note=Isoform 1 and isoform 2 are both localized in the mitochondrion. [UniProt] |
| Calculated MW | 39 kDa |
