ARG43456
anti-SLC29A3 / ENT3 antibody
anti-SLC29A3 / ENT3 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes SLC29A3 / ENT3 |
|---|---|
| Tested Reactivity | Ms, Rat |
| Predict Reactivity | Hu |
| Tested Application | IHC-P, WB |
| Specificity | This SLC29A3 / ENT antibody is predicted to not cross-react with other SLC29 proteins. |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | SLC29A3 / ENT3 |
| Antigen Species | Human |
| Immunogen | A 19 amino acid peptide within aa. N-terminal of Human SLC29A3 / ENT3. |
| Conjugation | Un-conjugated |
| Protein Full Name | Equilibrative nucleoside transporter 3 |
| Alternate Names | Equilibrative nucleoside transporter 3; ENT3; HJCD; PHID; HCLAP; Solute carrier family 29 member 3; UNQ717/PRO1380; hENT3 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Observed Size | 50-70 kDa (70 kda might be protein with PTM) |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | PBS and 0.02% Sodium azide. |
| Preservative | 0.02% Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q80WK7 Rat Equilibrative nucleoside transporter 3 Swiss-port # Q99P65 Mouse Equilibrative nucleoside transporter 3 |
|---|---|
| Gene Symbol | SLC29A3 |
| Gene Full Name | solute carrier family 29 member 3 |
| Background | This gene encodes a nucleoside transporter. The encoded protein plays a role in cellular uptake of nucleosides, nucleobases, and their related analogs. Mutations in this gene have been associated with H syndrome, which is characterized by cutaneous hyperpigmentation and hypertrichosis, hepatosplenomegaly, heart anomalies, and hypogonadism. A related disorder, PHID (pigmented hypertrichosis with insulin-dependent diabetes mellitus), has also been associated with mutations at this locus. Alternatively spliced transcript variants have been described.[provided by RefSeq, Mar 2010] |
| Function | Mediates both influx and efflux of nucleosides across the membrane (equilibrative transporter). Mediates transport of adenine, adenosine and uridine, as well as several nucleoside analog drugs, such as anticancer and antiviral agents, including cladribine, cordycepin, tubercidin and AZT. Does not transport hypoxanthine.[provided by uniprot] |
| Cellular Localization | Endosome, Lysosome, Membrane |
| Calculated MW | 51.8 kDa |
| PTM | Glycoprotein, Phosphoprotein |
