ARG43097
anti-SLC2A8 / GLUT8 antibody
anti-SLC2A8 / GLUT8 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes SLC2A8 / GLUT8 |
|---|---|
| Tested Reactivity | Hu, Rat |
| Predict Reactivity | Ms, Hm |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | SLC2A8 / GLUT8 |
| Antigen Species | Mouse |
| Immunogen | Synthetic peptide corresponding to aa. 461-477 of Mouse SLC2A8 / GLUT8. (ETKGRTLEQVTAHFEGR) |
| Conjugation | Un-conjugated |
| Alternate Names | GLUTX1; Solute carrier family 2, facilitated glucose transporter member 8; Glucose transporter type X1; GLUT-8; Glucose transporter type 8; GLUT8 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Positive Control | Rat testis and Human placenta | ||||||
| Observed Size | ~ 52 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl, 0.05% Thimerosal, 0.05% Sodium azide and 5% BSA. |
| Preservative | 0.05% Thimerosal and 0.05% Sodium azide |
| Stabilizer | 5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q9JJZ1 Rat Solute carrier family 2, facilitated glucose transporter member 8 Swiss-port # Q9NY64 Human Solute carrier family 2, facilitated glucose transporter member 8 |
|---|---|
| Gene Symbol | SLC2A8 |
| Gene Full Name | solute carrier family 2 (facilitated glucose transporter), member 8 |
| Background | This gene belongs to the solute carrier 2A family, which includes intracellular glucose transporters. Based on sequence comparison, the glucose transporters are grouped into three classes and this gene is a member of class II. The encoded protein, like other members of the family, contains several conserved residues and motifs and 12 transmembrane domains with both amino and carboxyl ends being on the cytosolic side of the membrane. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Nov 2012] |
| Function | Insulin-regulated facilitative hexose transporter that mediates the transport of glucose and fructose. Also able to mediate the transport of dehydroascorbate. [UniProt] |
| Cellular Localization | Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Note=Principally intracellular. May move between intracellular vesicles and the plasma membrane. The dileucine internalization motif is critical for intracellular sequestration (By similarity). [UniProt] |
| Calculated MW | 52 kDa |
