ARG59872
anti-SLC4A7 antibody
anti-SLC4A7 antibody for Western blot and Mouse
Overview
| Product Description | Rabbit Polyclonal antibody recognizes SLC4A7 |
|---|---|
| Tested Reactivity | Ms |
| Predict Reactivity | Hu |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | SLC4A7 |
| Antigen Species | Human |
| Immunogen | Recombinant fusion protein corresponding to aa. 240-400 of Human SLC4A7 (NP_003606.3). |
| Conjugation | Un-conjugated |
| Alternate Names | SBC2; NBC3; NBC2; NBCN1; Solute carrier family 4 member 7; Sodium bicarbonate cotransporter 2b; Bicarbonate transporter; 3; SLC4A6; Sodium bicarbonate cotransporter 3; Sodium bicarbonate cotransporter 2; Electroneutral Na/HCO |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | Mouse liver | ||||
| Observed Size | 160 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | SLC4A7 |
|---|---|
| Gene Full Name | solute carrier family 4, sodium bicarbonate cotransporter, member 7 |
| Background | This locus encodes a sodium bicarbonate cotransporter. The encoded transmembrane protein appears to transport sodium and bicarbonate ions in a 1:1 ratio, and is thus considered an electroneutral cotransporter. The encoded protein likely plays a critical role in regulation of intracellular pH involved in visual and auditory sensory transmission. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Apr 2012] |
| Function | Electroneutral sodium- and bicarbonate-dependent cotransporter with a Na(+):HCO3(-) 1:1 stoichiometry. Regulates intracellular pH and may play a role in bicarbonate salvage in secretory epithelia. May also have an associated sodium channel activity. [UniProt] |
| Cellular Localization | Basolateral cell membrane; Multi-pass membrane protein. Apical cell membrane; Multi-pass membrane protein. Cell projection, stereocilium. Note=Also described at the apical cell membrane. Localizes to the stereocilia of cochlear outer hair cells and to the lateral membrane of cochlear inner hair cells (By similarity). [UniProt] |
| Calculated MW | 136 kDa |
