ARG42095
anti-SLC6A8 antibody
anti-SLC6A8 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse
Overview
| Product Description | Goat Polyclonal antibody recognizes SLC6A8 |
|---|---|
| Tested Reactivity | Hu, Ms |
| Predict Reactivity | Cow, Rat, Dog, Pig |
| Tested Application | IHC-P, WB |
| Host | Goat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | SLC6A8 |
| Antigen Species | Human |
| Immunogen | Synthetic peptide around the internal region of Human SLC6A8. (ASLANLTCDQLADRR) (NP_005620.1; NP_001136277.1; NP_001136278.1) |
| Conjugation | Un-conjugated |
| Alternate Names | Solute carrier family 6 member 8; CCDS1; CT1; CRT; Creatine transporter 1; CRTR; CTR5; Sodium- and chloride-dependent creatine transporter 1 |
Application Instructions
| Application Suggestion |
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| Application Note | IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
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| Observed Size | ~ 70 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified |
| Buffer | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 0.5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P48029 Human Sodium- and chloride-dependent creatine transporter 1 Swiss-port # Q8VBW1 Mouse Sodium- and chloride-dependent creatine transporter 1 |
|---|---|
| Gene Symbol | SLC6A8 |
| Gene Full Name | solute carrier family 6 (neurotransmitter transporter), member 8 |
| Background | The protein encoded by this gene is a plasma membrane protein whose function is to transport creatine into and out of cells. Defects in this gene can result in X-linked creatine deficiency syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008] |
| Function | Required for the uptake of creatine in muscles and brain. [UniProt] |
| Cellular Localization | Membrane; Multi-pass membrane protein. [UniProt] |
| Calculated MW | 71 kDa |
