ARG64200

anti-SLC7A11 / xCT antibody

anti-SLC7A11 / xCT antibody for ICC/IF and Human

Ferroptosis/Oxytosis Study antibody

Overview

Product Description Goat Polyclonal antibody recognizes SLC7A11 / xCT
Tested Reactivity Hu
Tested Application ICC/IF
Host Goat
Clonality Polyclonal
Isotype IgG
Target Name SLC7A11 / xCT
Antigen Species Human
Immunogen C-KGQTQNFKDAFSGRD
Conjugation Un-conjugated
Alternate Names xCT; CCBR1; Cystine/glutamate transporter; Solute carrier family 7 member 11; Amino acid transport system xc-; Calcium channel blocker resistance protein CCBR1

Application Instructions

Application Suggestion
Tested Application Dilution
ICC/IF10 µg/ml
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Buffer Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
Preservative 0.02% Sodium azide
Stabilizer 0.5% BSA
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 23657 Human SLC7A11

Swiss-port # Q9UPY5 Human Cystine/glutamate transporter

Background This gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc(-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death. [provided by RefSeq, Sep 2011]
Highlight Related products:
SLC7A11 antibodies; SLC7A11 Duos / Panels; Anti-Goat IgG secondary antibodies;
Related news:
Ferroptosis/Oxytosis Antibody Panel is launched
Therapeutic strategies against PDAC
Research Area Ferroptosis/Oxytosis Study antibody
Calculated MW 55 kDa