ARG65037
anti-SLC7A5 / LAT1 antibody
anti-SLC7A5 / LAT1 antibody for Western blot and Human
Metabolism antibody; Signaling Transduction antibody
Overview
Product Description | Goat Polyclonal antibody recognizes SLC7A5 / LAT1 |
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Tested Reactivity | Hu |
Predict Reactivity | Dog |
Tested Application | WB |
Host | Goat |
Clonality | Polyclonal |
Isotype | IgG |
Target Name | SLC7A5 / LAT1 |
Antigen Species | Human |
Immunogen | C-RHRKPELERPIKVN |
Conjugation | Un-conjugated |
Alternate Names | MPE16; LAT1; CD98; D16S469E; Solute carrier family 7 member 5; 4F2LC; E16; Large neutral amino acids transporter small subunit 1; 4F2 LC; y+ system cationic amino acid transporter; Integral membrane protein E16; 4F2 light chain; hLAT1; L-type amino acid transporter 1; CD98 light chain |
Application Instructions
Application Suggestion |
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Application Note | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
Form | Liquid |
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Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
Buffer | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
Preservative | 0.02% Sodium azide |
Stabilizer | 0.5% BSA |
Concentration | 0.5 mg/ml |
Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Database Links |
Swiss-port # Q01650 Human Large neutral amino acids transporter small subunit 1 |
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Gene Symbol | SLC7A5 |
Gene Full Name | solute carrier family 7 (amino acid transporter light chain, L system), member 5 |
Function | Sodium-independent, high-affinity transport of large neutral amino acids such as phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc. Involved in cellular amino acid uptake. Acts as an amino acid exchanger. Involved in the transport of L-DOPA across the blood-brain barrier, and that of thyroid hormones triiodothyronine (T3) and thyroxine (T4) across the cell membrane in tissues such as placenta. Plays a role in neuronal cell proliferation (neurogenesis) in brain. Involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine or D,L-homocysteine complexes, and hence plays a role in metal ion homeostasis and toxicity. Involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane. May play an important role in high-grade gliomas. Mediates blood-to-retina L-leucine transport across the inner blood-retinal barrier which in turn may play a key role in maintaining large neutral amino acids as well as neurotransmitters in the neural retina. Acts as the major transporter of tyrosine in fibroblasts. [UniProt] |
Research Area | Metabolism antibody; Signaling Transduction antibody |
Calculated MW | 55 kDa |