ARG66898
anti-SLCO1A2 / OATP1A2 antibody
anti-SLCO1A2 / OATP1A2 antibody for Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes SLCO1A2 / OATP1A2 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | SLCO1A2 / OATP1A2 |
| Antigen Species | Human |
| Immunogen | Synthetic peptide between aa. 251-300 of Human SLCO1A2 / OATP1A2. |
| Conjugation | Un-conjugated |
| Alternate Names | OATP-A; Organic anion-transporting polypeptide 1; OATP1A2; OATP; Sodium-independent organic anion transporter; SLC21A3; OATP-1; Solute carrier organic anion transporter family member 1A2; Solute carrier family 21 member 3 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | HeLa, A549, AD293 and HepG2 | ||||
| Observed Size | 70-75 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | PBS, 0.02% Sodium azide, 50% Glycerol and 0.5% BSA. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol and 0.5% BSA |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P46721 Human Solute carrier organic anion transporter family member 1A2 |
|---|---|
| Gene Symbol | SLCO1A2 |
| Gene Full Name | solute carrier organic anion transporter family, member 1A2 |
| Background | This gene encodes a sodium-independent transporter which mediates cellular uptake of organic ions in the liver. Its substrates include bile acids, bromosulphophthalein, and some steroidal compounds. The protein is a member of the SLC21A family of solute carriers. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Dec 2008] |
| Function | Mediates the Na(+)-independent transport of organic anions such as sulfobromophthalein (BSP) and conjugated (taurocholate) and unconjugated (cholate) bile acids (By similarity). Selectively inhibited by the grapefruit juice component naringin. [UniProt] |
| Cellular Localization | Cell membrane; Multi-pass membrane protein. [UniProt] |
| Calculated MW | 74 kDa |
