ARG44935
anti-SMC2 antibody
anti-SMC2 antibody for Western blot and Mouse
Overview
| Product Description | Rat Monoclonal antibody recognizes SMC2 |
|---|---|
| Tested Reactivity | Ms |
| Tested Application | WB |
| Host | Rat |
| Clonality | Monoclonal |
| Isotype | IgG2a |
| Target Name | SMC2 |
| Antigen Species | Mouse |
| Conjugation | Un-conjugated |
| Alternate Names | SMC2; Structural Maintenance Of Chromosomes 2; HCAP-E; SMC2L1; CAP-E; SMC2 (Structural Maintenance Of Chromosomes 2, Yeast)-Like 1; Structural Maintenance Of Chromosomes Protein 2; Chromosome-Associated Protein E; XCAP-E Homolog; SMC Protein 2; SMC-2; CAPE; Structural Maintenance Of Chromosomes (SMC) Family Member, Chromosome-Associated Protein E; SMC2 Structural Maintenance Of Chromosomes 2-Like 1 (Yeast) |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Protein A purification |
| Buffer | PBS with 0.09% sodium azide |
| Preservative | 0.09% sodium azide |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | SMC2 |
|---|---|
| Gene Full Name | Structural Maintenance Of Chromosomes 2 |
| Background | Predicted to enable ATP binding activity; chromatin binding activity; and single-stranded DNA binding activity. Involved in mitotic chromosome condensation. Located in condensed chromosome; cytoplasm; and nuclear lumen. Part of condensin complex. [provided by Alliance of Genome Resources, Apr 2022] |
| Function | Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. [UniProt] |
| Cellular Localization | Chromosome, Cytoplasm, Nucleus. [UniProt] |
| PTM | Acetylation. [UniProt] |
