ARG44938
anti-SNRPB antibody
anti-SNRPB antibody for IHC-Formalin-fixed paraffin-embedded sections and Human
Overview
| Product Description | Mouse Monoclonal antibody recognizes SNRPB |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Target Name | SNRPB |
| Antigen Species | Human |
| Epitope | ILCDCDEFRK IKPKNSKQAE REEKRVLGLV LLRGENLVSM TVEGPPPKDT GIARVPLAGA AGGPGIGRAA GRGIPAGVPM |
| Conjugation | Un-conjugated |
| Alternate Names | SNRPB; Small Nuclear Ribonucleoprotein Polypeptides B And B1; Sm-B/B'; SnRNP-B; COD; SmB/SmB'; SNRPB1; Small Nuclear Ribonucleoprotein-Associated Proteins B And B'; Sm Protein B/B'; SmB/B'; Small Nuclear Ribonucleoprotein Polypeptides B And B'; Small Nuclear Ribonucleoprotein Polypeptide B; B Polypeptide Of Sm Protein; Sm-B/Sm-B'; CCMS |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Protein A purification |
| Buffer | PBS with 0.09% sodium azide |
| Preservative | 0.09% sodium azide |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | SNRPB |
|---|---|
| Gene Full Name | Small Nuclear Ribonucleoprotein Polypeptides B And B1 |
| Background | The protein encoded by this gene is one of several nuclear proteins that are found in common among U1, U2, U4/U6, and U5 small ribonucleoprotein particles (snRNPs). These snRNPs are involved in pre-mRNA splicing, and the encoded protein may also play a role in pre-mRNA splicing or snRNP structure. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding different isoforms (B and B') have been found for this gene. [provided by RefSeq, Jul 2008] |
| Function | As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing. [UniProt] |
| Cellular Localization | Cytoplasm, Nucleus, Spliceosome. [UniProt] |
| PTM | Methylation. [UniProt] |
