ARG63639
anti-SORL1 / SorLA antibody
anti-SORL1 / SorLA antibody for ICC/IF and Human
Neuroscience antibody; Signaling Transduction antibody
Overview
| Product Description | Goat Polyclonal antibody recognizes SORL1 / SorLA |
|---|---|
| Tested Reactivity | Hu |
| Predict Reactivity | Ms, Rat, Cow, Dog |
| Tested Application | ICC/IF |
| Host | Goat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | SORL1 / SorLA |
| Antigen Species | Human |
| Immunogen | C-TGFSDDVPMVIA |
| Conjugation | Un-conjugated |
| Alternate Names | SorLA-1; SorLA; LRP9; LR11; C11orf32; SORLA; gp250; Sorting protein-related receptor containing LDLR class A repeats; LDLR relative with 11 ligand-binding repeats; Sortilin-related receptor; Low-density lipoprotein receptor relative with 11 ligand-binding repeats |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified from goat serum by antigen affinity chromatography. |
| Buffer | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 0.5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Background | This gene encodes a mosaic protein that belongs to at least two families: the vacuolar protein sorting 10 (VPS10) domain-containing receptor family, and the low density lipoprotein receptor (LDLR) family. The encoded protein also contains fibronectin type III repeats and an epidermal growth factor repeat. The encoded protein is translated as a preproprotein and likely plays roles in endocytosis and sorting. There may be an association between expression of this locus and Alzheimer's Disease.[provided by RefSeq, Sep 2010] |
| Research Area | Neuroscience antibody; Signaling Transduction antibody |
| Calculated MW | 248 kDa |
| PTM | The propeptide removed in the N-terminus may be cleaved by furin or homologous proteases. |
