ARG65308
anti-SRGAP2 antibody
anti-SRGAP2 antibody for ICC/IF,Western blot and Human,Rat
Neuroscience antibody; Signaling Transduction antibody
Overview
| Product Description | Goat Polyclonal antibody recognizes SRGAP2 |
|---|---|
| Tested Reactivity | Hu, Rat |
| Predict Reactivity | Ms, Cow, Dog |
| Tested Application | ICC/IF, WB |
| Specificity | This antibody is expected to recognize isoform a (NP_056141.2). |
| Host | Goat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | SRGAP2 |
| Antigen Species | Human |
| Immunogen | C-KQEDRQTPRSPDST |
| Conjugation | Un-conjugated |
| Alternate Names | FNBP2; SRGAP3; srGAP2; ARHGAP34; SLIT-ROBO Rho GTPase-activating protein 2; Formin-binding protein 2; Rho GTPase-activating protein 34; SRGAP2A |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|---|---|
| Application Note | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified from goat serum by antigen affinity chromatography. |
| Buffer | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 0.5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # D4A208 Rat SLIT-ROBO Rho GTPase-activating protein 2 Swiss-port # O75044 Human SLIT-ROBO Rho GTPase-activating protein 2 |
|---|---|
| Background | This locus encodes a member of the SLIT-ROBO Rho GTPase activating protein family. The encoded protein stimulates GTPase activity of Rac1, and plays a role in cortical neuron development. This locus has several paralogs on human chromosome 1 resulting from segmental duplication. While this locus itself is conserved among various species, the paralogs are found only in the genus Homo, and not in the genomes of non-human great apes. Alternatively spliced transcript variants have been described for this locus. [provided by RefSeq, Jul 2014] |
| Research Area | Neuroscience antibody; Signaling Transduction antibody |
| Calculated MW | 121 kDa |
| PTM | Methylation at Arg-927 is required for the stimulation of cell migration, dimerization and localization at the plasma membrane protrusions. |
