ARG57895

anti-SSBP1 antibody

anti-SSBP1 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation,Western blot and Human,Mouse

Overview

Product Description Rabbit Polyclonal antibody recognizes SSBP1
Tested Reactivity Hu, Ms
Tested Application ICC/IF, IHC-P, IP, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name SSBP1
Antigen Species Human
Immunogen Recombinant fusion protein corresponding to aa. 1-148 of Human SSBP1 (NP_001243442.1).
Conjugation Un-conjugated
Alternate Names SSBP; mtSSB; PWP1-interacting protein 17; MtSSB; SOSS-B1; Mt-SSB; Single-stranded DNA-binding protein, mitochondrial

Application Instructions

Application Suggestion
Tested Application Dilution
ICC/IF1:50 - 1:100
IHC-P1:50 - 1:200
IP1:50 - 1:200
WB1:500 - 1:2000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control SW620
Observed Size 15 kDa

Properties

Form Liquid
Purification Affinity purified.
Buffer PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
Preservative 0.02% Sodium azide
Stabilizer 50% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 381760 Mouse SSBP1

GeneID: 6742 Human SSBP1

Swiss-port # Q04837 Human Single-stranded DNA-binding protein, mitochondrial

Swiss-port # Q9CYR0 Mouse Single-stranded DNA-binding protein, mitochondrial

Gene Symbol SSBP1
Gene Full Name single-stranded DNA binding protein 1, mitochondrial
Background SSBP1 is a housekeeping gene involved in mitochondrial biogenesis (Tiranti et al., 1995 [PubMed 7789991]). It is also a subunit of a single-stranded DNA (ssDNA)-binding complex involved in the maintenance of genome stability (Huang et al., 2009) [PubMed 19683501].[supplied by OMIM, Feb 2010]
Function This protein binds preferentially and cooperatively to ss-DNA. Probably involved in mitochondrial DNA replication. Associates with mitochondrial DNA. [UniProt]
Cellular Localization Mitochondrion, Mitochondrion matrix, mitochondrion nucleoid. [UniProt]
Calculated MW 17 kDa