ARG42951

anti-SSR3 antibody

anti-SSR3 antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections,Immunocytochemistry and Human,Mouse,Rat

Overview

Product Description Rabbit Polyclonal antibody recognizes SSR3
Tested Reactivity Hu, Ms, Rat
Tested Application ICC, IHC-P, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name SSR3
Antigen Species Human
Immunogen Synthetic peptide corresponding to aa. 8-23 of Human SSR3. (KQQSEEDLLLQDFSRN)
Conjugation Un-conjugated
Alternate Names TRAPG; Translocon-associated protein subunit gamma; Signal sequence receptor subunit gamma; TRAP-gamma; SSR-gamma

Application Instructions

Application Suggestion
Tested Application Dilution
ICC1:200 - 1:1000
IHC-P1:200 - 1:1000
WB1:500 - 1:2000
Application Note IHC-P: Antigen Retrieval: Heat mediation was performed in Citrate buffer (pH 6.0) for 20 min.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Observed Size ~ 21 kDa

Properties

Form Liquid
Purification Affinity purification with immunogen.
Buffer 0.2% Na2HPO4, 0.9% NaCl, 0.05% Thimerosal, 0.05% Sodium azide and 5% BSA.
Preservative 0.05% Thimerosal and 0.05% Sodium azide
Stabilizer 5% BSA
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 67437 Mouse SSR3

GeneID: 6747 Human SSR3

GeneID: 81784 Rat SSR3

Gene Symbol SSR3
Gene Full Name signal sequence receptor, gamma (translocon-associated protein gamma)
Background The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR is comprised of four membrane proteins/subunits: alpha, beta, gamma, and delta. The first two are glycosylated subunits and the latter two are non-glycosylated subunits. This gene encodes the gamma subunit, which is predicted to span the membrane four times. [provided by RefSeq, Aug 2010]
Function TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins. [UniProt]
Cellular Localization Endoplasmic reticulum membrane; Multi-pass membrane protein. [UniProt]
Calculated MW 21 kDa