ARG57136

anti-ST13 / Hip antibody [5C6]

anti-ST13 / Hip antibody [5C6] for Western blot,Flow cytometry,ICC/IF and Human

Overview

Product Description Mouse Monoclonal antibody [5C6] recognizes ST13 / Hip
Tested Reactivity Hu
Tested Application FACS, ICC/IF, WB
Host Mouse
Clonality Monoclonal
Clone 5C6
Isotype IgG2a, kappa
Target Name ST13 / Hip
Antigen Species Human
Immunogen Recombinant fragment around aa. 1-369 of Human ST13 / Hip
Conjugation Un-conjugated
Alternate Names HIP; SNC6; Putative tumor suppressor ST13; Progesterone receptor-associated p48 protein; Suppression of tumorigenicity 13 protein; HSPABP; Hsc70-interacting protein; HSPABP1; Protein FAM10A1; Hip; AAG2; HOP; P48; FAM10A1; PRO0786; Renal carcinoma antigen NY-REN-33; Aging-associated protein 2; FAM10A4

Application Instructions

Application Suggestion
Tested Application Dilution
FACSAssay-dependent
ICC/IFAssay-dependent
WB1:1000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purification with Protein A.
Buffer PBS (pH 7.4), 0.02% Sodium azide and 10% Glycerol.
Preservative 0.02% Sodium azide
Stabilizer 10% Glycerol
Concentration 1 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 6767 Human ST13

Swiss-port # P50502 Human Hsc70-interacting protein

Gene Symbol ST13
Gene Full Name suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)
Background The protein encoded by this gene is an adaptor protein that mediates the association of the heat shock proteins HSP70 and HSP90. This protein has been shown to be involved in the assembly process of glucocorticoid receptor, which requires the assistance of multiple molecular chaperones. The expression of this gene is reported to be downregulated in colorectal carcinoma tissue suggesting that it is a candidate tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2013]
Function One HIP oligomer binds the ATPase domains of at least two HSC70 molecules dependent on activation of the HSC70 ATPase by HSP40. Stabilizes the ADP state of HSC70 that has a high affinity for substrate protein. Through its own chaperone activity, it may contribute to the interaction of HSC70 with various target proteins (By similarity). [UniProt]
Calculated MW 41 kDa