ARG43443
anti-ST8sia1 antibody
anti-ST8sia1 antibody for Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes ST8sia1 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | ST8sia1 |
| Antigen Species | Human |
| Immunogen | Recombinant fusion protein corresponding to aa. 49-270 of Human ST8sia1 (NP_003025.1). |
| Conjugation | Un-conjugated |
| Alternate Names | SIAT8A; Sialyltransferase 8A; Ganglioside GT3 synthase; SIAT8; Alpha-2,8-sialyltransferase 8A; EC 2.4.99.8; Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase; Ganglioside GD3 synthase; ST8SiaI; GD3S; SIAT8-A; Sialyltransferase St8Sia I |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | SGC-7901 | ||||
| Observed Size | ~ 41 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q92185 Human Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase |
|---|---|
| Gene Symbol | ST8SIA1 |
| Gene Full Name | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 |
| Background | Gangliosides are membrane-bound glycosphingolipids containing sialic acid. Ganglioside GD3 is known to be important for cell adhesion and growth of cultured malignant cells. The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to GM3 to produce gangliosides GD3 and GT3. The encoded protein may be found in the Golgi apparatus and is a member of glycosyltransferase family 29. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2015] |
| Function | Involved in the production of gangliosides GD3 and GT3 from GM3; gangliosides are a subfamily of complex glycosphinglolipds that contain one or more residues of sialic acid. [UniProt] |
| Cellular Localization | Golgi apparatus membrane; Single-pass type II membrane protein. [UniProt] |
| Calculated MW | 41 kDa |
