ARG43443

anti-ST8sia1 antibody

anti-ST8sia1 antibody for Western blot and Human

Overview

Product Description Rabbit Polyclonal antibody recognizes ST8sia1
Tested Reactivity Hu
Tested Application WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name ST8sia1
Antigen Species Human
Immunogen Recombinant fusion protein corresponding to aa. 49-270 of Human ST8sia1 (NP_003025.1).
Conjugation Un-conjugated
Alternate Names SIAT8A; Sialyltransferase 8A; Ganglioside GT3 synthase; SIAT8; Alpha-2,8-sialyltransferase 8A; EC 2.4.99.8; Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase; Ganglioside GD3 synthase; ST8SiaI; GD3S; SIAT8-A; Sialyltransferase St8Sia I

Application Instructions

Application Suggestion
Tested Application Dilution
WB1:500 - 1:2000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control SGC-7901
Observed Size ~ 41 kDa

Properties

Form Liquid
Purification Affinity purified.
Buffer PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
Preservative 0.02% Sodium azide
Stabilizer 50% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 6489 Human ST8SIA1

Swiss-port # Q92185 Human Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase

Gene Symbol ST8SIA1
Gene Full Name ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
Background Gangliosides are membrane-bound glycosphingolipids containing sialic acid. Ganglioside GD3 is known to be important for cell adhesion and growth of cultured malignant cells. The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to GM3 to produce gangliosides GD3 and GT3. The encoded protein may be found in the Golgi apparatus and is a member of glycosyltransferase family 29. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2015]
Function Involved in the production of gangliosides GD3 and GT3 from GM3; gangliosides are a subfamily of complex glycosphinglolipds that contain one or more residues of sialic acid. [UniProt]
Cellular Localization Golgi apparatus membrane; Single-pass type II membrane protein. [UniProt]
Calculated MW 41 kDa