ARG63948

anti-STAM2 antibody

anti-STAM2 antibody for Western blot and Human

Signaling Transduction antibody

Overview

Product Description Goat Polyclonal antibody recognizes STAM2
Tested Reactivity Hu
Predict Reactivity Ms, Dog
Tested Application WB
Specificity No cross-reaction expected with STAM1.
Host Goat
Clonality Polyclonal
Isotype IgG
Target Name STAM2
Antigen Species Human
Immunogen C-QSIDPTDSKPDSQD
Conjugation Un-conjugated
Alternate Names STAM-2; STAM2B; STAM2A; Signal transducing adapter molecule 2; Hrs-binding protein; Hbp

Application Instructions

Application Suggestion
Tested Application Dilution
WB1 - 3 µg/ml
Application Note WB: Recommend incubate at RT for 1h.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Buffer Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
Preservative 0.02% Sodium azide
Stabilizer 0.5% BSA
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 10254 Human STAM2

Swiss-port # O75886 Human Signal transducing adapter molecule 2

Background The protein encoded by this gene is closely related to STAM, an adaptor protein involved in the downstream signaling of cytokine receptors, both of which contain a SH3 domain and the immunoreceptor tyrosine-based activation motif (ITAM). Similar to STAM, this protein acts downstream of JAK kinases, and is phosphorylated in response to cytokine stimulation. This protein and STAM thus are thought to exhibit compensatory effects on the signaling pathway downstream of JAK kinases upon cytokine stimulation. [provided by RefSeq, Jul 2008]
Research Area Signaling Transduction antibody
Calculated MW 58 kDa
PTM Phosphorylated in response to IL-2, GM-CSF, EGF and PDGF.