ARG63948
anti-STAM2 antibody
anti-STAM2 antibody for Western blot and Human
Signaling Transduction antibody
Overview
| Product Description | Goat Polyclonal antibody recognizes STAM2 |
|---|---|
| Tested Reactivity | Hu |
| Predict Reactivity | Ms, Dog |
| Tested Application | WB |
| Specificity | No cross-reaction expected with STAM1. |
| Host | Goat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | STAM2 |
| Antigen Species | Human |
| Immunogen | C-QSIDPTDSKPDSQD |
| Conjugation | Un-conjugated |
| Alternate Names | STAM-2; STAM2B; STAM2A; Signal transducing adapter molecule 2; Hrs-binding protein; Hbp |
Application Instructions
| Application Suggestion |
|
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|---|---|---|---|---|---|
| Application Note | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Buffer | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 0.5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # O75886 Human Signal transducing adapter molecule 2 |
|---|---|
| Background | The protein encoded by this gene is closely related to STAM, an adaptor protein involved in the downstream signaling of cytokine receptors, both of which contain a SH3 domain and the immunoreceptor tyrosine-based activation motif (ITAM). Similar to STAM, this protein acts downstream of JAK kinases, and is phosphorylated in response to cytokine stimulation. This protein and STAM thus are thought to exhibit compensatory effects on the signaling pathway downstream of JAK kinases upon cytokine stimulation. [provided by RefSeq, Jul 2008] |
| Research Area | Signaling Transduction antibody |
| Calculated MW | 58 kDa |
| PTM | Phosphorylated in response to IL-2, GM-CSF, EGF and PDGF. |
