ARG51555
anti-STAT6 phospho (Thr645) antibody
anti-STAT6 phospho (Thr645) antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Human
Gene Regulation antibody; Signaling Transduction antibody
Overview
| Product Description | Rabbit Polyclonal antibody recognizes STAT6 phospho (Thr645) |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | STAT6 |
| Antigen Species | Human |
| Immunogen | Peptide sequence around phosphorylation site of threonine 645 (P-A-T(p)-I-K) derived from Human STAT6. |
| Conjugation | Un-conjugated |
| Alternate Names | D12S1644; STAT6B; STAT6C; Signal transducer and activator of transcription 6; IL-4-STAT; IL-4 Stat |
Application Instructions
| Application Suggestion |
|
||||||
|---|---|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Antibodies were produced by immunizing rabbits with KLH-conjugated synthetic phosphopeptide. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. In addition, non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Buffer | PBS (without Mg2+ and Ca2+, pH 7.4), 150mM NaCl, 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P42226 Human Signal transducer and activator of transcription 6 |
|---|---|
| Gene Symbol | STAT6 |
| Gene Full Name | signal transducer and activator of transcription 6, interleukin-4 induced |
| Background | Carries out a dual function: signal transduction and activation of transcription. Involved in interleukin-4 signalling. |
| Function | Carries out a dual function: signal transduction and activation of transcription. Involved in IL4/interleukin-4- and IL3/interleukin-3-mediated signaling. [UniProt] |
| Research Area | Gene Regulation antibody; Signaling Transduction antibody |
| Calculated MW | 94 kDa |
| PTM | Tyrosine phosphorylated following stimulation by IL4/interleukin-4 and IL3/interleukin-3 (By similarity). Dephosphorylation on tyrosine residues by PTPN2 negatively regulates the IL4/interleukin-4 mediated signaling. |
