ARG43421
anti-STK38 / NDR1 antibody
anti-STK38 / NDR1 antibody for Western blot and Human,Rat
Overview
| Product Description | Goat Polyclonal antibody recognizes STK38 / NDR1 |
|---|---|
| Tested Reactivity | Hu, Rat |
| Predict Reactivity | Cow, Dog, Pig |
| Tested Application | WB |
| Host | Goat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | STK38 / NDR1 |
| Antigen Species | Human |
| Immunogen | Synthetic peptide around the C-terminus of Human STK38 / NDR1 (NP_009202.1). (C-KPTVATSNHPET) |
| Conjugation | Un-conjugated |
| Alternate Names | Nuclear Dbf2-related kinase 1; NDR1 protein kinase; Serine/threonine-protein kinase 38; EC 2.7.11.1; NDR; NDR1 |
Application Instructions
| Application Suggestion |
|
||||
|---|---|---|---|---|---|
| Application Note | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
||||
| Positive Control | Human spleen | ||||
| Observed Size | ~ 55 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified |
| Buffer | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 0.5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q15208 Human Serine/threonine-protein kinase 38 |
|---|---|
| Gene Symbol | STK38 |
| Gene Full Name | serine/threonine kinase 38 |
| Background | This gene encodes a member of the AGC serine/threonine kinase family of proteins. The kinase activity of this protein is regulated by autophosphorylation and phosphorylation by other upstream kinases. This protein has been shown to function in the cell cycle and apoptosis. This protein has also been found to regulate the protein stability and transcriptional activity of the MYC oncogene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015] |
| Function | Negative regulator of MAP3K1/2 signaling. Converts MAP3K2 from its phosphorylated form to its non-phosphorylated form and inhibits autophosphorylation of MAP3K2. [UniProt] |
| Cellular Localization | Nucleus. Cytoplasm. [UniProt] |
| Calculated MW | 54 kDa |
| PTM | ISGylated. Phosphorylated by STK3/MST2 and this is enhanced by MOBKL1B. [UniProt] |
