ARG64221

anti-STRA antibody

anti-STRA antibody for Western blot and Mouse,Rat

Controls and Markers antibody; Developmental Biology antibody; Metabolism antibody; Signaling Transduction antibody

Overview

Product Description Goat Polyclonal antibody recognizes STRA
Tested Reactivity Ms, Rat
Tested Application WB
Host Goat
Clonality Polyclonal
Isotype IgG
Target Name STRA
Antigen Species Rat
Immunogen C-QAFRKAALTSAKAN
Conjugation Un-conjugated
Alternate Names MCOPCB8; PP14296; Stimulated by retinoic acid gene 6 protein homolog; MCOPS9

Application Instructions

Application Suggestion
Tested Application Dilution
WB1 - 2 µg/ml
Application Note WB: Recommend incubate at RT for 1h.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Buffer Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
Preservative 0.02% Sodium azide
Stabilizer 0.5% BSA
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 20897 Mouse STRA6

GeneID: 363071 Rat STRA6

Swiss-port # O70491 Mouse Stimulated by retinoic acid gene 6 protein

Swiss-port # Q4QR83 Rat Stimulated by retinoic acid gene 6 protein homolog

Gene Symbol Stra6
Gene Full Name stimulated by retinoic acid 6
Background The protein encoded by this gene is a membrane protein involved in the metabolism of retinol. The encoded protein acts as a receptor for retinol/retinol binding protein complexes. This protein removes the retinol from the complex and transports it across the cell membrane. Defects in this gene are a cause of syndromic microphthalmia type 9 (MCOPS9). Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]
Function May act as a high-affinity cell-surface receptor for the complex retinol-retinol binding protein (RBP/RBP4). Acts by removing retinol from RBP/RBP4 and transports it across the plasma membrane, where it can be metabolized. This mechanism does not depend on endocytosis. Binds to RBP/RBP4 with high affinity. Increases cellular retinol uptake from the retinol-RBP complex (By similarity). [UniProt]
Research Area Controls and Markers antibody; Developmental Biology antibody; Metabolism antibody; Signaling Transduction antibody
Calculated MW 74 kDa