ARG59818
anti-SUCLA2 antibody
anti-SUCLA2 antibody for ICC/IF,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes SUCLA2 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | SUCLA2 |
| Antigen Species | Human |
| Immunogen | Recombinant fusion protein corresponding to aa. 1-180 of Human SUCLA2 (NP_003841.1). |
| Conjugation | Un-conjugated |
| Alternate Names | MTDPS5; SCS-betaA; Succinyl-CoA synthetase beta-A chain; A-BETA; EC 6.2.1.5; Succinyl-CoA ligase [ADP-forming] subunit beta, mitochondrial; Renal carcinoma antigen NY-REN-39; ATP-specific succinyl-CoA synthetase subunit beta |
Application Instructions
| Predict Reactivity Note | Rat | ||||||
|---|---|---|---|---|---|---|---|
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Positive Control | Mouse heart and HeLa | ||||||
| Observed Size | 50 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q9P2R7 Human Succinyl-CoA ligase [ADP-forming] subunit beta, mitochondrial Swiss-port # Q9Z2I9 Mouse Succinyl-CoA ligase [ADP-forming] subunit beta, mitochondrial |
|---|---|
| Gene Symbol | SUCLA2 |
| Gene Full Name | succinate-CoA ligase, ADP-forming, beta subunit |
| Background | Succinyl-CoA synthetase (SCS) is a mitochondrial matrix enzyme that acts as a heterodimer, being composed of an invariant alpha subunit and a substrate-specific beta subunit. The protein encoded by this gene is an ATP-specific SCS beta subunit that dimerizes with the SCS alpha subunit to form SCS-A, an essential component of the tricarboxylic acid cycle. SCS-A hydrolyzes ATP to convert succinate to succinyl-CoA. Defects in this gene are a cause of myopathic mitochondrial DNA depletion syndrome. A pseudogene of this gene has been found on chromosome 6. [provided by RefSeq, Jul 2008] |
| Function | Catalyzes the ATP-dependent ligation of succinate and CoA to form succinyl-CoA. [UniProt] |
| Cellular Localization | Mitochondrion. [UniProt] |
| Calculated MW | 50 kDa |
