ARG44948
anti-SULT1A1 / STP antibody
anti-SULT1A1 / STP antibody for IHC-Formalin-fixed paraffin-embedded sections and Human
Overview
| Product Description | Mouse Monoclonal antibody recognizes SULT1A1 / STP |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG2b |
| Target Name | SULT1A1 / STP |
| Antigen Species | Human |
| Epitope | PLEYVKGVPL IKYFAEALGP LQSFQARPDD LLISTYPKSG TTWVSQILDM IYQGGDLEKC HRAPIFMRVP FLEFKAPGIP SGMETLKDTP APRLLKTHLP LALLPQTLLD QKVKVVYVAR NAKDVAVSYY HFYHMAKVHP EPGTWDSFLE KFMVGEVSYG SWYQHVQEWW ELSRTHPVLY LFYEDMKENP KREIQKILEF VGRSLPEETV DFVVQHTSFK EMKKNPMTNY TTVPQEFMDH SISPFMRKGM AGDWKTTFTV AQNERFDADY AEKMAGCSLS |
| Conjugation | Un-conjugated |
| Alternate Names | SULT1A1; Sulfotransferase Family 1A Member 1; P-PST; STP1; STP; Sulfotransferase Family, Cytosolic, 1A, Phenol-Preferring, Member 1; Phenol-Sulfating Phenol Sulfotransferase 1; Aryl Sulfotransferase 1; Sulfotransferase 1A1; HAST1/HAST2; EC 2.8.2.1; P-PST 1; Ts-PST; ST1A1; ST1A3; Thermostable Phenol Sulfotransferase1; Thermostable Phenol Sulfotransferase; Phenol Sulfotransferase 1; EC 2.8.2; TSPST1; PST |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Protein A purification |
| Buffer | PBS with 0.09% sodium azide |
| Preservative | 0.09% sodium azide |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | SULT1A1 |
|---|---|
| Gene Full Name | Sulfotransferase Family 1A Member 1 |
| Background | Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene encodes one of two phenol sulfotransferases with thermostable enzyme activity. Multiple alternatively spliced variants that encode two isoforms have been identified for this gene. [provided by RefSeq, Jul 2008] |
| Function | May play a role in gut microbiota-host metabolic interaction. O-sulfonates 4-ethylphenol (4-EP), a dietary tyrosine-derived metabolite produced by gut bacteria. The product 4-EPS crosses the blood-brain barrier and may negatively regulate oligodendrocyte maturation and myelination, affecting the functional connectivity of different brain regions associated with the limbic system. [Uniprot] |
| Cellular Localization | Cytoplasm. [Uniprot] |
| PTM | Phosphoprotein. [Uniprot] |
