ARG44345
anti-SUPV3L1 / SUV3 antibody
anti-SUPV3L1 / SUV3 antibody for ICC/IF,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes SUPV3L1 / SUV3 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | SUPV3L1 / SUV3 |
| Antigen Species | Human |
| Immunogen | Human SUPV3L1 / SUV3 recombinant fusion protein (a.a. sequence: 577-786). |
| Conjugation | Un-conjugated |
| Alternate Names | SUPV3L1; Suv3 Like RNA Helicase; SUV3; ATP-Dependent RNA Helicase SUPV3L1, Mitochondrial; SUV3-Like Protein 1; Suppressor Of Var1, 3-Like 1 (S. Cerevisiae); Suppressor Of Var1 (S.Cerevisiae) 3-Like 1; Suppressor Of Var1 3-Like Protein 1; Suppressor Of Var1, 3-Like 1(SUV3); Suppressor Of Var1, 3-Like 1; SUV3-Like Helicase; EC 3.6.4.13; EC 3.6.1 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS, 0.02% sodium azide and 50% Glycerol. |
| Preservative | 0.02% sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | SUPV3L1 |
| Gene Full Name | Suv3 Like RNA Helicase |
| Background | Enables helicase activity; nucleic acid binding activity; and protein homodimerization activity. Involved in several processes, including mitochondrial RNA metabolic process; mitochondrion morphogenesis; and positive regulation of mitochondrial RNA catabolic process. Located in mitochondrial nucleoid and nucleus. Part of mitochondrial degradosome. |
| Function | Major helicase player in mitochondrial RNA metabolism. Component of the mitochondrial degradosome (mtEXO) complex, that degrades 3' overhang double-stranded RNA with a 3'-to-5' directionality in an ATP-dependent manner. Involved in the degradation of non-coding mitochondrial transcripts (MT-ncRNA) and tRNA-like molecules. |
| Cellular Localization | Mitochondrion, Mitochondrion nucleoid, Nucleus |
| Calculated MW | 88 kDa |
| PTM | Acetylation, Phosphoprotein |
