ARG66477
anti-SUPV3L1 / SUV3 antibody
anti-SUPV3L1 / SUV3 antibody for Western blot and Human,Mouse
Overview
| Product Description | Rabbit Polyclonal antibody recognizes SUPV3L1 / SUV3 |
|---|---|
| Tested Reactivity | Hu, Ms |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | SUPV3L1 / SUV3 |
| Antigen Species | Human |
| Immunogen | Recombinant full length protein of Human SUPV3L1 / SUV3. |
| Conjugation | Un-conjugated |
| Alternate Names | SUPV3L1; SUV3; ATP-dependent RNA helicase SUPV3L1, mitochondrial; SUV3-like protein 1; EC 3.6.4.13; Suppressor of var1 3-like protein 1; SUV3L1 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | 0.42% Potassium phosphate (pH 7.3), 0.87% Sodium chloride, 0.01% Sodium azide and 30% Glycerol. |
| Preservative | 0.87% Sodium chloride |
| Stabilizer | 0.01% Sodium azide and 30% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q80YD1 Mouse ATP-dependent RNA helicase SUPV3L1, mitochondrial Swiss-port # Q8IYB8 Human ATP-dependent RNA helicase SUPV3L1, mitochondrial |
|---|---|
| Gene Symbol | SUPV3L1 |
| Gene Full Name | SUV3-like helicase |
| Function | Major helicase player in mitochondrial RNA metabolism. Component of the mitochondrial degradosome (mtEXO) complex, that degrades 3' overhang double-stranded RNA with a 3'-to-5' directionality in an ATP-dependent manner. ATPase and ATP-dependent multisubstrate helicase, able to unwind double-stranded (ds) DNA and RNA, and RNA/DNA heteroduplexes in the 5'-to-3' direction. Plays a role in the RNA surveillance system in mitochondria; regulates the stability of mature mRNAs, the removal of aberrantly formed mRNAs and the rapid degradation of non coding processing intermediates. Also implicated in recombination and chromatin maintenance pathways. May protect cells from apoptosis. Associates with mitochondrial DNA. [UniProt] |
| Cellular Localization | Nucleus. Mitochondrion matrix. Mitochondrion matrix, mitochondrion nucleoid. [UniProt] |
| Calculated MW | 88 kDa |
