ARG43648
anti-Secretogranin II antibody
anti-Secretogranin II antibody for ICC/IF,Western blot and Human,Rat
Neuroscience antibody
Overview
| Product Description | Rabbit Polyclonal antibody recognizes Secretogranin II |
|---|---|
| Tested Reactivity | Hu, Rat |
| Tested Application | ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | Secretogranin II |
| Antigen Species | Human |
| Immunogen | Recombinant protein fragment corresponding to a.a. 30-320 of Human secretogranin II (SCG2). |
| Conjugation | Un-conjugated |
| Protein Full Name | Secretogranin-2 |
| Alternate Names | EM66; Secretogranin II; CHGC; SgII; SN; Secretogranin-2; Chromogranin-C |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Observed Size | ~70 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS, 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | SCG2 |
| Gene Full Name | secretogranin II |
| Background | The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Studies in rodents suggest that the full-length protein, secretogranin II, is involved in the packaging or sorting of peptide hormones and neuropeptides into secretory vesicles. The full-length protein is cleaved to produce the active peptide secretoneurin, which exerts chemotaxic effects on specific cell types, and EM66, whose function is unknown. [provided by RefSeq, Jul 2008] |
| Function | Secretogranin-2 is a neuroendocrine secretory granule protein, which is the precursor for biologically active peptides. [UniProt] |
| Cellular Localization | Centromere; Chromosome; Nucleus |
| Research Area | Neuroscience antibody |
| Calculated MW | 71 kDa |
| PTM | O-glycosylated. |
