ARG40240
anti-Shroom 3 antibody
anti-Shroom 3 antibody for Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes Shroom 3 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | WB |
| Specificity | Shroom 3 antibody is human specific. At least four isoforms of Shroom 3 are known to exist; this antibody will detect all four isoforms. Shroom 3 antibody is predicted to not cross-react with other Shroom family members. |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | Shroom 3 |
| Antigen Species | Human |
| Immunogen | An 18 amino acid peptide within aa. 850 - 900 of Human Shroom 3. |
| Conjugation | Un-conjugated |
| Alternate Names | ShrmL; Shroom-related protein; hShrmL; Protein Shroom3; SHRM; MSTP013; APXL3 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | SK-N-SH cell |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | PBS and 0.02% Sodium azide |
| Preservative | 0.02% Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | SHROOM3 |
| Gene Full Name | shroom family member 3 |
| Background | This gene encodes a PDZ-domain-containing protein that belongs to a family of Shroom-related proteins. This protein may be involved in regulating cell shape in certain tissues. A similar protein in mice is required for proper neurulation. [provided by RefSeq, Jan 2011] |
| Function | Controls cell shape changes in the neuroepithelium during neural tube closure. Induces apical constriction in epithelial cells by promoting the apical accumulation of F-actin and myosin II, and probably by bundling stress fibers. Induces apicobasal cell elongation by redistributing gamma-tubulin and directing the assembly of robust apicobasal microtubule arrays (By similarity). [UniProt] |
| Cellular Localization | Cell junction, adherens junction. Cytoplasm, cytoskeleton. Note=Colocalizes with F-actin in stress fibers and adherens junctions. [UniProt] |
| Calculated MW | 217 kDa |
