ARG65166

anti-Stabilin 1 antibody

anti-Stabilin 1 antibody for IHC-Formalin-fixed paraffin-embedded sections and Human

Cell Biology and Cellular Response antibody; Signaling Transduction antibody

Overview

Product Description Goat Polyclonal antibody recognizes Stabilin 1
Tested Reactivity Hu
Predict Reactivity Cow, Dog, Pig
Tested Application IHC-P
Host Goat
Clonality Polyclonal
Isotype IgG
Target Name Stabilin 1
Antigen Species Human
Immunogen C-DFPDTQRILTVK
Conjugation Un-conjugated
Alternate Names STAB-1; FEX1; Fasciclin, EGF-like, laminin-type EGF-like and link domain-containing scavenger receptor 1; FEEL-1; Stabilin-1; FELE-1; MS-1 antigen; CLEVER-1

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P3 - 5 µg/ml
Application Note IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0).
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Buffer Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
Preservative 0.02% Sodium azide
Stabilizer 0.5% BSA
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 23166 Human STAB1

Swiss-port # Q9NY15 Human Stabilin-1

Background This gene encodes a large, transmembrane receptor protein which may function in angiogenesis, lymphocyte homing, cell adhesion, or receptor scavenging. The protein contains 7 fasciclin, 16 epidermal growth factor (EGF)-like, and 2 laminin-type EGF-like domains as well as a C-type lectin-like hyaluronan-binding Link module. The protein is primarily expressed on sinusoidal endothelial cells of liver, spleen, and lymph node. The receptor has been shown to endocytose ligands such as low density lipoprotein, Gram-positive and Gram-negative bacteria, and advanced glycosylation end products. Supporting its possible role as a scavenger receptor, the protein rapidly cycles between the plasma membrane and early endosomes. [provided by RefSeq, Jul 2008]
Research Area Cell Biology and Cellular Response antibody; Signaling Transduction antibody
Calculated MW 275 kDa