ARG54073
anti-Syntenin 1 antibody
anti-Syntenin 1 antibody for Western blot and Human
Neuroscience antibody
Overview
Product Description | Mouse Monoclonal antibody recognizes Syntenin 1 |
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Tested Reactivity | Hu |
Tested Application | WB |
Host | Mouse |
Clonality | Monoclonal |
Isotype | IgG2b |
Target Name | Syntenin 1 |
Antigen Species | Human |
Immunogen | Purified recombinant Human Syntenin 1 protein fragments expressed in E.coli. |
Conjugation | Un-conjugated |
Alternate Names | SYCL; MDA-9; MDA9; Pro-TGF-alpha cytoplasmic domain-interacting protein 18; Syndecan-binding protein 1; TACIP18; Scaffold protein Pbp1; ST1; Syntenin-1; Melanoma differentiation-associated protein 9 |
Application Instructions
Application Suggestion |
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Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
Observed Size | 32 kDa |
Properties
Form | Liquid |
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Purification | Affinity purified |
Buffer | 0.1M Tris-Glycine (pH 7.4), 150 mM NaCl, 0.2% Sodium azide and 50% Glycerol |
Preservative | 0.2% Sodium azide |
Stabilizer | 50% Glycerol |
Concentration | 1 mg/ml |
Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Database Links | |
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Gene Symbol | SDCBP |
Gene Full Name | syndecan binding protein (syntenin) |
Background | Seems to function as an adapter protein. In adherens junctions may function to couple syndecans to cytoskeletal proteins or signaling components. Seems to couple transcription factor SOX4 to the IL-5 receptor (IL5RA). May also play a role in vesicular trafficking. Seems to be required for the targeting of TGFA to the cell surface in the early secretory pathway. |
Function | Seems to function as an adapter protein. In adherens junctions may function to couple syndecans to cytoskeletal proteins or signaling components. Seems to couple transcription factor SOX4 to the IL-5 receptor (IL5RA). May also play a role in vesicular trafficking. Seems to be required for the targeting of TGFA to the cell surface in the early secretory pathway. [UniProt] |
Cellular Localization | Nucleus. Cytoplasm. Mitochondrion. Note: Cytoplasmic during the interphase. Reversibly translocated from cytoplasm to nucleus when phosphorylated before G2-M transition when associated with cyclin-B1. Accumulates in mitochondria in G2-arrested cells upon DNA-damage. |
Research Area | Neuroscience antibody |
Calculated MW | 32 kDa |
PTM | Phosphorylated on tyrosine residues. |