ARG54073

anti-Syntenin 1 antibody

anti-Syntenin 1 antibody for Western blot and Human

Neuroscience antibody

Overview

Product Description Mouse Monoclonal antibody recognizes Syntenin 1
Tested Reactivity Hu
Tested Application WB
Host Mouse
Clonality Monoclonal
Isotype IgG2b
Target Name Syntenin 1
Antigen Species Human
Immunogen Purified recombinant Human Syntenin 1 protein fragments expressed in E.coli.
Conjugation Un-conjugated
Alternate Names SYCL; MDA-9; MDA9; Pro-TGF-alpha cytoplasmic domain-interacting protein 18; Syndecan-binding protein 1; TACIP18; Scaffold protein Pbp1; ST1; Syntenin-1; Melanoma differentiation-associated protein 9

Application Instructions

Application Suggestion
Tested Application Dilution
WB1:1000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Observed Size 32 kDa

Properties

Form Liquid
Purification Affinity purified
Buffer 0.1M Tris-Glycine (pH 7.4), 150 mM NaCl, 0.2% Sodium azide and 50% Glycerol
Preservative 0.2% Sodium azide
Stabilizer 50% Glycerol
Concentration 1 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 6386 Human SDCBP

Swiss-port # O00560 Human Syntenin-1

Gene Symbol SDCBP
Gene Full Name syndecan binding protein (syntenin)
Background Seems to function as an adapter protein. In adherens junctions may function to couple syndecans to cytoskeletal proteins or signaling components. Seems to couple transcription factor SOX4 to the IL-5 receptor (IL5RA). May also play a role in vesicular trafficking. Seems to be required for the targeting of TGFA to the cell surface in the early secretory pathway.
Function Seems to function as an adapter protein. In adherens junctions may function to couple syndecans to cytoskeletal proteins or signaling components. Seems to couple transcription factor SOX4 to the IL-5 receptor (IL5RA). May also play a role in vesicular trafficking. Seems to be required for the targeting of TGFA to the cell surface in the early secretory pathway. [UniProt]
Cellular Localization Nucleus. Cytoplasm. Mitochondrion. Note: Cytoplasmic during the interphase. Reversibly translocated from cytoplasm to nucleus when phosphorylated before G2-M transition when associated with cyclin-B1. Accumulates in mitochondria in G2-arrested cells upon DNA-damage.
Research Area Neuroscience antibody
Calculated MW 32 kDa
PTM Phosphorylated on tyrosine residues.