ARG41812

anti-TBR1 antibody

anti-TBR1 antibody for Western blot and Human,Mouse,Rat

Overview

Product Description Rabbit Polyclonal antibody recognizes TBR1
Tested Reactivity Hu, Ms, Rat
Tested Application WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name TBR1
Antigen Species Human
Immunogen Synthetic peptide of Human TBR1.
Conjugation Un-conjugated
Alternate Names T-box brain protein 1; TBR-1; T-brain-1; TES-56

Application Instructions

Application Suggestion
Tested Application Dilution
WB1:500 - 1:2000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control Human fetal brain
Observed Size ~ 75 kDa

Properties

Form Liquid
Purification Affinity purified.
Buffer PBS (pH 7.4), 150 mM NaCl, 0.02% Sodium azide and 50% Glycerol.
Preservative 0.02% Sodium azide
Stabilizer 50% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 10716 Human TBR1

GeneID: 21375 Mouse TBR1

Swiss-port # Q16650 Human T-box brain protein 1

Swiss-port # Q64336 Mouse T-box brain protein 1

Gene Symbol TBR1
Gene Full Name T-box, brain, 1
Background This gene is a member of a conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. A similar protein has been disrupted in mice and shown to be critical for early cortical development, and causes loss of projection neurons in the olfactory bulbs and olfactory cortex. The C-terminal region this similar protein was found to be necessary and sufficient for association with the guanylate kinase domain of calcium/calmodulin-dependent serine protein kinase. [provided by RefSeq, Jul 2008]
Function Probable transcriptional regulator involved in developmental processes. Required for normal brain development. [UniProt]
Cellular Localization Nucleus. [UniProt]
Calculated MW 74 kDa