ARG55833

anti-TCEAL1 antibody

anti-TCEAL1 antibody for Western blot and Human

Overview

Product Description Rabbit Polyclonal antibody recognizes TCEAL1
Tested Reactivity Hu
Tested Application WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name TCEAL1
Antigen Species Human
Immunogen KLH-conjugated synthetic peptide corresponding to aa. 1-30 (N-terminus) of Human TCEAL1.
Conjugation Un-conjugated
Alternate Names pp21; Transcription elongation factor A protein-like 1; Nuclear phosphoprotein p21/SIIR; Transcription elongation factor S-II protein-like 1; TCEA-like protein 1; p21; WEX9; SIIR

Application Instructions

Application Suggestion
Tested Application Dilution
WB1:1000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control RD

Properties

Form Liquid
Purification Purification with Protein A and immunogen peptide.
Buffer PBS and 0.09% (W/V) Sodium azide
Preservative 0.09% (W/V) Sodium azide
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 9338 Human TCEAL1

Swiss-port # Q15170 Human Transcription elongation factor A protein-like 1

Gene Symbol TCEAL1
Gene Full Name transcription elongation factor A (SII)-like 1
Background This gene encodes a member of the transcription elongation factor A (SII)-like (TCEAL) gene family. Members of this family may function as nuclear phosphoproteins that modulate transcription in a promoter context-dependent manner. The encoded protein is similar to transcription elongation factor A/transcription factor SII and contains a zinc finger-like motif as well as a sequence related to the transcription factor SII Pol II-binding region. It may exert its effects via protein-protein interactions with other transcriptional regulators rather than via direct binding of DNA. Multiple family members are located on the X chromosome. Alternative splicing results in multiple transcript variants encoding a single isoform. [provided by RefSeq, Jul 2008]
Function May be involved in transcriptional regulation. Modulates various viral and cellular promoters in a promoter context-dependent manner. For example, transcription from the FOS promoter is increased, while Rous sarcoma virus (RSV) long terminal repeat (LTR) promoter activity is repressed. Does not bind DNA directly. [UniProt]
Cellular Localization Nucleus.
Calculated MW 18 kDa
PTM Phosphorylation of Ser-36 and Ser-37 is critical for transcriptional repression.