ARG41310
anti-TDGF1 / Cripto 1 antibody
anti-TDGF1 / Cripto 1 antibody for ICC/IF,Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes TDGF1 / Cripto 1 |
|---|---|
| Tested Reactivity | Hu |
| Predict Reactivity | Ms, Rat |
| Tested Application | ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | TDGF1 / Cripto 1 |
| Antigen Species | Human |
| Immunogen | A 17 amino acid peptide within aa. 40 - 90 of Human TDGF1. |
| Conjugation | Un-conjugated |
| Alternate Names | CRGF; Teratocarcinoma-derived growth factor 1; Cripto-1 growth factor; CR; CRIPTO; Epidermal growth factor-like cripto protein CR1 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Positive Control | 293 cells | ||||||
| Observed Size | 15-21 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | PBS and 0.02% Sodium azide |
| Preservative | 0.02% Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P13385 Human Teratocarcinoma-derived growth factor 1 |
|---|---|
| Gene Symbol | TDGF1 |
| Gene Full Name | teratocarcinoma-derived growth factor 1 |
| Background | This gene encodes an epidermal growth factor-related protein that contains a cripto, FRL-1, and cryptic domain. The encoded protein is an extracellular, membrane-bound signaling protein that plays an essential role in embryonic development and tumor growth. Mutations in this gene are associated with forebrain defects. Pseudogenes of this gene are found on chromosomes 2, 3, 6, 8, 19 and X. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010] |
| Function | Could play a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm. [UniProt] |
| Cellular Localization | Cell membrane; Lipid-anchor, GPI-anchor. Secreted. Note=Released from the cell membrane by GPI cleavage. [UniProt] |
| Calculated MW | 21 kDa |
