ARG42376
anti-TFG / TRK-fused gene protein antibody [TFG-03]
anti-TFG / TRK-fused gene protein antibody [TFG-03] for Immunoprecipitation,Western blot,ICC/IF and Human
Overview
| Product Description | Mouse Monoclonal antibody [TFG-03] recognizes TFG / TRK-fused gene protein |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ICC/IF, IP, WB |
| Specificity | The mouse monoclonal antibody TFG-03 recognizes TFG, an approximately 50 kDa intracellular protein with regulatory functions. |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | TFG-03 |
| Isotype | IgG2b |
| Target Name | TFG / TRK-fused gene protein |
| Antigen Species | Human |
| Immunogen | Human recombinant protein Trx-his-TFG. |
| Conjugation | Un-conjugated |
| Alternate Names | TRKT3; HMSNP; SPG57; Protein TFG; TF6; TRK-fused gene protein |
Application Instructions
| Application Suggestion |
|
||||||||
|---|---|---|---|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A. |
| Buffer | PBS and 15 mM Sodium azide. |
| Preservative | 15 mM Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | TFG |
| Gene Full Name | TRK-fused gene |
| Background | There are several documented fusion oncoproteins encoded partially by this gene. This gene also participates in several oncogenic rearrangements resulting in anaplastic lymphoma and mixoid chondrosarcoma, and may play a role in the NF-kappaB pathway. Multiple transcript variants have been found for this gene. [provided by RefSeq, Sep 2010] |
| Function | Plays a role in the normal dynamic function of the endoplasmic reticulum (ER) and its associated microtubules (PubMed:23479643, PubMed:27813252). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus (PubMed:21478858). [UniProt] |
| Cellular Localization | Endoplasmic reticulum. Note=Localizes to endoplasmic reticulum exit site (ERES) (PubMed:27813252). [UniProt] |
| Calculated MW | 43 kDa |
