ARG42376

anti-TFG / TRK-fused gene protein antibody [TFG-03]

anti-TFG / TRK-fused gene protein antibody [TFG-03] for Immunoprecipitation,Western blot,ICC/IF and Human

Overview

Product Description Mouse Monoclonal antibody [TFG-03] recognizes TFG / TRK-fused gene protein
Tested Reactivity Hu
Tested Application ICC/IF, IP, WB
Specificity The mouse monoclonal antibody TFG-03 recognizes TFG, an approximately 50 kDa intracellular protein with regulatory functions.
Host Mouse
Clonality Monoclonal
Clone TFG-03
Isotype IgG2b
Target Name TFG / TRK-fused gene protein
Antigen Species Human
Immunogen Human recombinant protein Trx-his-TFG.
Conjugation Un-conjugated
Alternate Names TRKT3; HMSNP; SPG57; Protein TFG; TF6; TRK-fused gene protein

Application Instructions

Application Suggestion
Tested Application Dilution
ICC/IFAssay-dependent
IPAssay-dependent
WBAssay-dependent
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purification with Protein A.
Buffer PBS and 15 mM Sodium azide.
Preservative 15 mM Sodium azide
Concentration 1 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 10342 Human TFG

Swiss-port # Q92734 Human Protein TFG

Gene Symbol TFG
Gene Full Name TRK-fused gene
Background There are several documented fusion oncoproteins encoded partially by this gene. This gene also participates in several oncogenic rearrangements resulting in anaplastic lymphoma and mixoid chondrosarcoma, and may play a role in the NF-kappaB pathway. Multiple transcript variants have been found for this gene. [provided by RefSeq, Sep 2010]
Function Plays a role in the normal dynamic function of the endoplasmic reticulum (ER) and its associated microtubules (PubMed:23479643, PubMed:27813252). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus (PubMed:21478858). [UniProt]
Cellular Localization Endoplasmic reticulum. Note=Localizes to endoplasmic reticulum exit site (ERES) (PubMed:27813252). [UniProt]
Calculated MW 43 kDa