ARG64509
anti-TGFBR3 antibody
anti-TGFBR3 antibody for Flow cytometry,ICC/IF and Human
Overview
| Product Description | Goat Polyclonal antibody recognizes TGFBR3 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | FACS, ICC/IF |
| Host | Goat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | TGFBR3 |
| Antigen Species | Human |
| Immunogen | Synthetic peptide around the internal region of Human TGFBR3. (NP_003234.2; NP_001182613.1) (C-TKSIRDDIPSTQGN) |
| Conjugation | Un-conjugated |
| Alternate Names | TGFBR3; transforming growth factor; beta receptor III; BGCAN; betaglycan; betaglycan proteoglycan |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified |
| Buffer | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 0.5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q03167 Human Transforming growth factor beta receptor type 3 |
|---|---|
| Gene Symbol | TGFBR3 |
| Gene Full Name | transforming growth factor beta receptor 3 |
| Background | This locus encodes the transforming growth factor (TGF)-beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.[provided by RefSeq, Sep 2010] |
| Function | Binds to TGF-beta. Could be involved in capturing and retaining TGF-beta for presentation to the signaling receptors. [UniProt] |
| Cellular Localization | Secreted, extracellular space. Cell membrane; Single-pass type I membrane protein. Note=Exists both as a membrane-bound form and as soluble form in serum and in the extracellular matrix. [UniProt] |
| Calculated MW | 93 kDa |
| PTM | Extensively modified by glycosaminoglycan groups (GAG). [UniProt] |
