ARG64233
anti-TGM2 / Tissue transglutaminase antibody
anti-TGM2 / Tissue transglutaminase antibody for Western blot and Human
Cell Biology and Cellular Response antibody; Cell Death antibody; Immune System antibody; Metabolism antibody; Signaling Transduction antibody
Overview
| Product Description | Goat Polyclonal antibody recognizes TGM2 / Tissue transglutaminase |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | WB |
| Specificity | This antibody is expected to recognise isoform a (NP_004604.2) only. |
| Host | Goat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | TGM2 / Tissue transglutaminase |
| Antigen Species | Human |
| Immunogen | C-NFESDKLKAVKGFR |
| Conjugation | Un-conjugated |
| Alternate Names | TG2; G-ALPHA-h; TGase H; Transglutaminase C; TGase C; HEL-S-45; Transglutaminase-2; Tissue transglutaminase; C; TGase-2; TGC; Protein-glutamine gamma-glutamyltransferase 2; TG; Transglutaminase H; GNAH; EC 2.3.2.13 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Buffer | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 0.5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P21980 Human Protein-glutamine gamma-glutamyltransferase 2 |
|---|---|
| Background | Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| Research Area | Cell Biology and Cellular Response antibody; Cell Death antibody; Immune System antibody; Metabolism antibody; Signaling Transduction antibody |
| Calculated MW | 77 kDa |
