ARG41106

anti-TGM5 antibody

anti-TGM5 antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Human,Mouse,Rat

Overview

Product Description Rabbit Polyclonal antibody recognizes TGM5
Tested Reactivity Hu, Ms, Rat
Tested Application IHC-P, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name TGM5
Antigen Species Human
Immunogen Recombinant fusion protein corresponding to aa. 461-720 of Human TGM5 (NP_963925.2).
Conjugation Un-conjugated
Alternate Names Transglutaminase-5; TGM6; TGMX; TGase-5; TGX; TGase X; Protein-glutamine gamma-glutamyltransferase 5; X; TGASE5; PSS2; TG; TGASEX; EC 2.3.2.13; Transglutaminase X

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P1:50 - 1:200
WB1:500 - 1:2000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control Rat heart
Observed Size 81 kDa

Properties

Form Liquid
Purification Affinity purified.
Buffer PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
Preservative 0.02% Sodium azide
Stabilizer 50% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 74176 Mouse TGM5

GeneID: 9333 Human TGM5

Swiss-port # O43548 Human Protein-glutamine gamma-glutamyltransferase 5

Swiss-port # Q9D7I9 Mouse Protein-glutamine gamma-glutamyltransferase 5

Gene Symbol TGM5
Gene Full Name transglutaminase 5
Background This gene encodes a member of the transglutaminase family. The encoded protein catalyzes formation of protein cross-links between glutamine and lysine residues, often resulting in stabilization of protein assemblies. This reaction is calcium dependent. Mutations in this gene have been associated with acral peeling skin syndrome. [provided by RefSeq, Oct 2009]
Function Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins. Contributes to the formation of the cornified cell envelope of keratinocytes. [UniProt]
Cellular Localization Cytoplasm. Note=Associated with intermediate filaments. [UniProt]
Calculated MW 81 kDa